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Author | No. of eyes | Mean follow-up in months (range) | Visual acuity evolution (logMAR) | Anatomical evolution | Comments |
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Theodossiadis et al. [23] | 41 | 37.1 (25–54) | 73% of eyes: stable VA 27% of eyes: VA loss (19.5% eyes lost 5–15 letters) | Diameter increased by 13.7% Foveal thickness decreased by 10.3% | Metamorphopsia 75.6% eyes: initial 95% eyes: final No cataract progression |
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Bottoni et al. [24] | 34 10 eyes with “thicker ERM” | 18 (6–24) | Mean VA stable VA slightly worse at baseline | Diameter stable in 79% eyes Decrease of foveal thickness: 3% at 24 months Thinner foveas at baseline 30% IS/OS defects (vs 12.5% in “typical ERM”) | 1/10 developed FTMH (compared with 1/24 in eyes with “typical ERM”) |
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Celik et al. [25] | 21 | 21.6 | Initial VA 0.51 Final VA 0.55 | 3 had IS/OS defects at baseline ⟶ 2 developed defects | |
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Pang et al. [15] | 145 42.7% with LHEP 57.3% ERM without LHEP | 26 | Initial VA 0.51 5% of eyes lost 0.3 lines Initial VA 0.33 4% of eyes lost 0.3 lines | 18% anatomical progression 88% IS/OS disruption 13% anatomical progression 24% IS/OS disruption | No significant difference in the percentage of eyes that lost 0.3 logMAR lines |
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Zampedri et al. [26] | 189 eyes Intact IS/OS line 66.1% Intact ELM 78.3% 38% “atypical ERM” | 68 eyes—12 months 35 eyes—24 months | VA has not changed significantly VA slightly worse in “atypical ERM” | Mean diameter increased significantly in both groups Foveal thickness decreased significantly in the “atypical ERM” group | |
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Purtskhvanidze et al. [27] | 17 | 111 (75–155) | Initial VA 0.2 Final VA 0.3 | Decrease of foveal thickness Increased diameter Increased IS/OS defects | 2/3 of LMH and MPH remain stable after 8.3 years |
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Marques et al. [28] | 49 53% LHEP | 32 | | No differences in anatomical progression in patients with or without LHEP | |
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Compera et al. [29] | 34 (100% with LHEP) | 40.5 | | IS/OS defects: 65% at baseline 85% at final visit | Loss of VA correlates with maximal LMH diameter and IS/OS defects |
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