Epidemiological Study of Uveal Melanoma from US Surveillance, Epidemiology, and End Results Program (2010–2015)
Table 1
Sex-stratified uveal melanoma age-adjusted incidence rates and IRRs from the SEER 18 registries research database, 2010–2015 (2631 cases included).
Characteristic
Male
Female
Female-male IRR (95% CI)
Overall IRR (95% CI)
No. of patientsa
Incidence rateb
IRR (95% CI)
No. of patients
Incidence rateb
IRR (95% CI)
Total
1405
5.306
Reference
1226
4.076
0.768 (0.710–0.832)
0.768 (0.710–0.832)
0.768 (0.710–0.832)
Age range
<60
603
2.573
Reference
506
2.129
Reference
0.827 (0.732–0.935)
Reference
60–80
689
19.148
7.441 (6.643–8.336)
599
14.366
6.749 (5.970–7.629)
0.750 (0.670–0.840)
7.060 (6.498–7.669)
>80
113
18.973
7.373 (5.973–9.033)
121
11.825
5.555 (4.506–6.807)
0.623 (0.478–0.814)
6.194 (5.351–7.146)
Race
White
1348
6.415
Reference
1185
5.114
Reference
0.797 (0.735–0.864)
Reference
Black
14
0.535
0.083 (0.042–0.146)
11
0.360
0.070 (0.034–0.127)
0.673 (0.267–1.687)
0.076 (0.048–0.114)
AIAN
2
0.456
0.071 (0.009–0.298)
5
1.354
0.265 (0.079–0.636)
2.968 (0.405–31.448)
0.164 (0.061–0.350)
API
18
0.701
0.109 (0.064–0.175)
14
0.443
0.087 (0.047–0.148)
0.632 (0.286–1.374)
0.098 (0.066–0.139)
Origin
Non-Hispanic
1347
5.969
Reference
1137
4.424
Reference
0.741 (0.683–0.805)
Reference
Hispanic
58
1.596
0.267 (0.197–0.353)
89
2.008
0.454 (0.359–0.567)
1.258 (0.879–1.823)
0.350 (0.291–0.416)
Primary laterality
Right
658
0.247
Reference
625
0.208
Reference
0.839 (0.749–0.940)
Reference
Left
745
0.282
1.141 (1.023–1.272)
595
0.198
0.953 (0.848–1.071)
0.701 (0.627–0.784)
1.045 (0.966–1.131)
Abbreviation: SEER, Surveillance, Epidemiology, and End Results; IRR, incidence rates ratios; AIAN, American Indian/Alaska Native; API, Asian or Pacific Islander. aTotal amount may not be 2631 due to exclusion of cases with unknown information. bIncidence rates are based on the number of persons diagnosed as having uveal melanoma per 1,000,000 person-years, age adjusted using the 2000 US population standard. Bold letter indicates that measurements are statistically significant compared with references ().
