Clinical Presentations and Outcomes of Retinoblastoma Patients in relation to the Advent of New Multimodal Treatments: A 12-Year Report from Single Tertiary Referral Institute in Thailand

Table 1

Retinoblastoma chemotherapy regimens [37, 43].

Agents/course interval	Regimens
	Standard dose (BW < 12 kg)	Intensified dose for ICRB groups D and E (BW < 12 kg)	High dose for extraocular retinoblastoma
Vincristine	1.5 mg/m^2/day on day 1 (0.05 mg/kg/day)	1.5 mg/m^2/day on day 1 (0.05 mg/kg/day)	0.025 mg/kg/day on day 1
Etoposide	150 mg/m^2/day on days 1-2 (5 mg/kg/day)	180 mg/m^2/day on days 1-2 (6 mg/kg/day)	12 mg/kg/day on days 1-2
Carboplatin	560 mg/m^2/day on day 1 (18.6 mg/kg/day)	420 mg/m^2/day on days 1-2 (14 mg/kg/day)	28 mg/kg/day on day 1
Course interval	Continue every 4 weeks for a total of six cycles	Continue every 4 weeks for a total of six cycles	Continue every 3 weeks for a total of six cycles

ICRB = International Classification of Retinoblastoma.