Research Article

Renin-Angiotensin System Inhibitor Usage and Age-Related Macular Degeneration among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey, 2005–2008

Table 2

Age- and multivariate-adjusted ORs for any AMD among the study population.

Age-adjustedMultivariate-adjusted
OR (95% CI)OR (95% CI)

RASI usage1.17 (0.88–1.57)0.271.32 (0.83–2.08)0.22
RASI category
 ACEI1.31 (0.98–1.74)0.061.37 (0.94–2.00)0.09
 ARB0.93 (0.59–1.48)0.761.22 (0.53–2.79)0.62

Adjusted for age, stroke history, cataract surgery history, heart disease, and HDL. Except participants taking both ACEI and ARB. Reference group: RASI nonusers.. OR: odds ratio; AMD: age-related macular degeneration; CI: confidence interval; RASI: renin-angiotensin system inhibitor; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; HDL: high-density lipoprotein.