Renin-Angiotensin System Inhibitor Usage and Age-Related Macular Degeneration among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey, 2005–2008

Table 3

Multivariate-adjusted ORs for AMD among the hypertensive population.

	Early AMD		Late AMD
	OR (95% CI)		OR (95% CI)
RASI usage	1.28 (0.76–2.15)	0.33	1.76 (0.62–5.02)	0.27
RASI category^†
ACEI	1.27 (0.80–2.05)	0.28	2.50 (0.86–7.30)	0.09
ARB	1.32 (0.57–3.01)	0.49	2.50 (0.86–7.30)	0.29

^†Except participants taking both ACEI and ARB. Adjusted for age, stroke history, cataract surgery history, heart disease, and HDL. Reference group: RASI nonusers. OR: odds ratio; AMD: age-related macular degeneration; CI: confidence interval; RASI: renin-angiotensin system inhibitor; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; HDL: high-density lipoprotein.