Effect of Repeated Intravitreal Ranibizumab and Aflibercept Injections on the Cornea in Patients with Age-Related Macular Degeneration

Table 1

Morphometric analysis of the corneal endothelial cell density (ECD), the percentage of hexagonal cells (% Hex), the coefficient of variation of cell size (CoV), and central corneal thickness (CCT) in the treated eye before and after ranibizumab injections (RI).

Ranibizumab injection (RI)
	Before 1^st RI; Mean ± SD	After 1^st RI; Mean ± SD	After 2^nd RI; Mean ± SD	After 3^rd RI; Mean ± SD	6 m after 1^st RI; Mean ± SD
ECD (cells/mm^2)	2397.1 ± 459.3	2389.4 ± 459.2	2386.1 ± 467.5	2378.1 ± 475.3	2356.8 ± 460.4
% Hex	53.7 ± 8.6%	51.6 ± 8.5%	50.6 ± 8.1%	49.8 ± 9.1%	46.2 ± 8.9%
CoV	36.7 ± 6.3	37.1 ± 5.7	38.8 ± 6.6	37.7 ± 6.4	38.1 ± 6.3
CCT (µm)	551.1 ± 33.7	551.1 ± 31.2	555.7 ± 34.8	552.7 ± 32.7	555.1 ± 36.2