Effect of Repeated Intravitreal Ranibizumab and Aflibercept Injections on the Cornea in Patients with Age-Related Macular Degeneration

Table 3

Morphometric analysis of the corneal endothelial cell density (ECD), the percentage of hexagonal cells (% Hex), the coefficient of variation of cell size (CoV), and central corneal thickness (CCT) in the treated eye before and after aflibercept injections (AI).

Aflibercept injection (AI)
	Before 1^st AI; Mean ± SD	After 1^st AI; Mean ± SD	After 2^nd AI; Mean ± SD	After 3^rd AI; Mean ± SD	6 m after 1^st AI; Mean ± SD
ECD (cells/mm^2)	2488.3 ± 492.9	2455.7 ± 497.7	2425.5 ± 496.1	2402.3 ± 488.5	2348.1 ± 473.5
% Hex	52.6 ± 8.7	51.5 ± 7.9	51.4 ± 7.1	50.4 ± 7.9	49.3 ± 7.8
CoV	36.1 ± 6.7	366.3 ± 5.9	36.4 ± 5.8	37.1 ± 5.3	37.6 ± 5.5
CCT (µm)	556.1 ± 40.7	559.9 ± 41.4	555.6 ± 43.1	555.3 ± 45.9	552.1 ± 48.2