Research Article

Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia

Table 4

Effect of environmental and genetic factors on myopia occurrence.

Parents with or without myopiaDiopters in children (quartile)Myopia rate in childrenEGI
25th50th75th

With myopia−0.500.400.9026.3%0.125
Without myopia0.000.601.1013.8%
One-side parent with myopia−0.100.500.9018.7%
P<0.001<0.001

EGI comprehensively reflects both the effects of genetic factors and environmental factors.