The Role of Th17 Cells and IL-17 in Th2 Immune Responses of Allergic Conjunctivitis

Figure 2

1. CD40 and CD86 signaling on DC appears to be critical in the induction of Th17 cells. 2. IL-23 supports the maintenance of Th17 cell function. 3. IL-6 and TGF-β produced by eosinophil and DC expression promote Th17 cell differentiation. 4. Activated Th2 cells can be directly transformed into Th17 cells.