Research Article
The Influence of Marital Status on the Survival of Patients with Uveal Melanoma
Table 2
Univariate and multivariate analysis for OS in uveal melanoma patients.
| Variables | Median OS (month) | Univariate analysis | Multivariate analysis | Log-rank χ2 | value | HR (95% CI) | value |
| Gender | | | | | <0.001 | Male | 44 | 7.138 | 0.008 | Reference | | Female | 47 | | | 0.770 (0.682, 0.870) | | Age at diagnosis | | 77.138 | <0.001 | | <0.001 | <40 | 51.5 | | | Reference | | 40–59 | 54 | | | 1.774 (1.208, 2.604) | 0.003 | 60–79 | 43 | | | 3.136 (2.150, 4.575) | <0.001 | ≥80 | 34 | | | 7.065 (4.762, 10.482) | <0.001 | Race | | 16.063 | 0.001 | | 0.001 | Black | 39 | | | Reference | | White | 45 | | | 2.307 (0.742, 7.178) | 0.149 | Others | 43.5 | | | 2.321 (0.670, 8.042) | 0.184 | Unknown | 74 | | | 0.561 (0.125, 2.514) | 0.450 | Diagnosis year | | 3.783 | 0.286 | | 0.058 | 2004–2006 | 109 | | | | | 2007–2009 | 80 | | | | 0.025 | 2010–2012 | 46 | | | | 0.023 | 2013–2015 | 15 | | | | 0.856 | Marital status | | 77.138 | <0.001 | | 0.003 | Married | 46 | | | Reference | | Single | 44 | | | 1.203 (1.005, 1.440) | 0.044 | Divorced/separated | 43 | | | 1.305 (1.065, 1.600) | 0.010 | Widowed | 41 | | | 1.300 (1.086, 1.556) | 0.004 | SEER stage | | 213.756 | <0.001 | | <0.001 | Localized | 45 | | | Reference | | Regional | 50 | | | 1.985 (1.703, 2.313) | <0.001 | Metastatic | 13 | | | 5.163 (3.681, 7.242) | <0.001 | Surgery | | 81.276 | <0.001 | | <0.001 | Yes | 38 | | | Reference | | No/unknown | 47 | | | 0.588 (0.523, 0.661) | <0.001 | Median household income | | 9.447 | 0.024 | | 0.145 | Quartile 1 | 45 | | | | | Quartile 2 | 42 | | | | 0.076 | Quartile 3 | 44.5 | | | | 0.970 | Quartile 4 | 49 | | | | 0.046 | Registry sites | | 4.391 | 0.222 | | 0.015 | West | 43 | | | Reference | | Midwest | 46.5 | | | 0.861 (0.715, 1.036) | 0.113 | South | 46 | | | 1.056 (0.904, 1.234) | 0.492 | Northeast | 54 | | | 0.796 (0.669, 0.947) | 0.010 |
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