Microcornea and Thickened Lens in Angle Closure following Nonsurgical Treatment of Retinopathy of Prematurity
Table 1
Baseline characteristics and management outcome of consecutive young angle closure patients with and without a history of treated retinopathy of prematurity (ROP).
With treated ROP, N = 11, 19 eyes
Full-term patients, N = 3, 6 eyes
value
Notes
Female, N (%)
9 (81.8%)
2 (66.7%)
0.50
Age at presentation (years), mean ± SD
11.9 ± 6.31
11.9 ± 4.0
1.0
Eyes with microcornea, N (%)
19 (100%)
0 (0%)
<0.0001
Eyes with pachyphakia, N (%)
19 (100%)
2 (33.3%)
0.0012
Biometry available
4 patients, 8 eyes
3 patients, 6 eyes
Age at biometry (years), mean ± SD
14.8 ± 7.43
13.8 ± 2.34
0.83
Anterior chamber depth (mm), mean ± SD
1.77 ± 0.17
2.72 ± 0.18
<0.0001
Lens thickness (mm), mean ± SD
5.20 ± 0.54
3.98 ± 0.20
0.0002
Eyes requiring IOP-lowering medications, N (%)
12 (63.2%)
4 (66.7%)
0.86
Eyes requiring IOP-lowering laser/surgery, N (%)
10 (52.6%)
4 (66.7%)
0.04
Age at most recent visit (years), mean ± SD
13.5 ± 2.76
16.5 ± 3.27
0.13
Most recent logMAR visual acuity, mean ± SD
0.77 ± 0.45
0.19 ± 0.13
0.0053†
Most recent intraocular pressure (mmHg), mean ± SD
13.5 ± 2.76
16.5 ± 3.27
<0.0001†
SD = standard deviation; logMAR = logarithm of minimum angle of resolution; †this difference becomes insignificant on sensitivity analysis using only one eye in bilaterally affected patients ( and for logMAR visual acuity and IOP, respectively). value <0.05.
