Atropine 0.01% for the Control of Myopia in Chinese Children: Effect on Accommodation Functions and Pupil Size

Table 1

Eligibility criteria for the study.

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Children aged 6 to 14 years

Refractive error of spherical equivalent between −0.50 D and −6.00 D^†‡

Astigmatism of −2.50 D or less^†

Best-corrected visual acuity of logMAR 0.1 or better in both eyes

No history of other ocular diseases (i.e., amblyopia, strabismus, cataract, glaucoma, and congenital retinal diseases)

In good general health with no history of significant cardiac, respiratory, or endocrine diseases

No allergy to atropine, tropicamide, and cyclopentolate

No current or previous use of atropine or pirenzepine, contact lenses, or other forms of treatment that might affect myopia progression

Willing to comply with the allocated treatment and follow-up schedule

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logMAR = logarithm of the minimum angle of resolution. ^†Refraction was measured with cycloplegicretinoscopy. ^‡Refractive error of the spherical equivalent was defined as spherical refraction plus half the cylinder refraction.