Clinical Study

Atropine 0.01% for the Control of Myopia in Chinese Children: Effect on Accommodation Functions and Pupil Size

Table 2

Baseline characteristics of the children in the two study groups.

Atropine groupControl group value
Mean (SD), n = 38Mean (SD), n = 25

Age (yr)8.7 (1.6)8.7 (1.8)0.89
Female, n (%)19 (50.0)11 (44.0)0.64
Spherical equivalent (D)−1.94 (1.17)−1.78 (1.15)0.39
Axial length (mm)24.21 (0.90)24.33 (0.64)0.12
Near BCVA (logMAR)0.00 (0.00)0.00 (0.00)
Distant BCVA (logMAR)0.01 (0.02)0.00 (0.01)0.70
Age at wearing spectacle (yr)8.2 (1.7)7.6 (1.7)0.23
Paternal myopia status, n (%)
 No myopia8 (21.1)2 (8.0)
 SE < 6.0 D23 (60.5)16 (64.0)0.32
 SE ≥ 6.0 D7 (18.4)7 (28.0)
Maternal myopia status, n (%)
 No myopia7 (18.4)6 (24.0)0.74
 SE < 6.0 D22 (57.9)12 (48.0)
 SE ≥ 6.0 D9 (23.7)7 (28.0)
Accommodation amplitude (D)
 Monocular9.3 (2.2)9.3 (2.8)0.73
 Binocular7.4 (2.2)7.3 (2.3)0.63
Accommodation facility (cpm)
 Monocular10.6 (2.9)10.9 (4.0)0.87
 Binocular8.7 (3.2)9.2 (4.0)0.54
Pupil diameter (mm)6.3 (1.0)6.3 (1.1)0.54
Near stereoacuity (log (seconds of arc))1.4 (0.2)1.4 (0.1)0.17
Intraocular pressure (mmHg)16.5 (2.8)15.4 (3.1)0.05

D = diopter; BCVA = best-corrected visual acuity; logMAR = logarithm of the minimum angle of resolution; cpm = cycles per minute.