Intravitreal Injections for Macular Edema Secondary to Retinal Vein Occlusion: Long-Term Functional and Anatomic Outcomes

Table 2

Mean BCVA and CMT and their changes at each annual time point for the whole population and for BRVO/CRVO subgroups (results are reported until the eighth year; subsequent FU is not included because of the small sample size).

		Number of eyes	BCVA logMar-mean (SD)	BCVA improvement logMar-mean (SD)	value	CMT μmmean (SD)	CMT improvement μm-mean (SD)	value
Baseline	Whole population	223	0.79 (0.71)	—	—	615.7 (257.5)	—	—
	BRVO	124	0.60 (0.53)	—	—	536.9 (212.5)	—	—
	CRVO	99	1.03 (0.84)	—	—	714.4 (275.4)	—	—
1 year	Whole population	223	0.62 (0.68)	0.16 (0.61)	<0.0001	401.04 (183.8)	214.6 (269.6)	<0.0001
	BRVO	124	0.43 (0.51)	0.17 (0.50)	<0.0001	355.2 (135.0)	181.7 (211.5)	<0.0001
	CRVO	99	0.88 (0.78)	0.16 (0.72)	0.0169	458.5 (218.3)	255.9 (324.7)	<0.0001
2 years	Whole population	189	0.63 (0.71)	0.12 (0.68)	0.009	376.4 (171.2)	229.0 (289.1)	<0.0001
	BRVO	114	0.40 (0.47)	0.17 (0.51)	0.0002	348.7 (139.7)	183.3 (243.5)	<0.0001
	CRVO	75	0.99 (0.85)	0.03 (0.87)	0.3652	418.1 (203.9)	297.9 (336.9)	<0.0001
3 years	Whole population	147	0.65 (0.73)	0.04 (0.70)	0.2588	367.1 (171.1)	232.1 (288.6)	<0.0001
	BRVO	94	0.47 (0.55)	0.10 (0.60)	0.0522	337.9 (147.9)	193.1 (236.6)	<0.0001
	CRVO	53	0.96 (0.89)	−0.07 (0.95)	0.3089	419.9 (197.4)	302.6 (356.1)	<0.0001
4 years	Whole population	115	0.60 (0.75)	0.06 (0.74)	0.1761	379.8 (196.2)	215.9 (273.1)	<0.0001
	BRVO	73	0.39 (0.48)	0.16 (0.48)	0.0029	340.8 (158.6)	181.7 (239.2)	<0.0001
	CRVO	42	0.96 (0.97)	−0.09 (1.04)	0.2726	449.0 (236.2)	276.6 (319.1)	<0.0001
5 years	Whole population	80	0.48 (0.62)	0.14 (0.58)	0.0183	344.6 (156.4)	241.5 (251.2)	<0.0001
	BRVO	52	0.40 (0.63)	0.08 (0.51)	0.1338	330.2 (154.3)	170.8 (201.8)	<0.0001
	CRVO	28	0.61 (0.59)	0.25 (0.69)	0.0341	369.8 (159.5)	365.8 (283.1)	<0.0001
6 years	Whole population	61	0.46 (0.57)	0.19 (0.59)	0.0079	332.8 (154.0)	255.5 (255.9)	<0.0001
	BRVO	41	0.32 (0.48)	0.20 (0.48)	0.0068	313.2 (149.4)	223.6 (227.1)	<0.0001
	CRVO	20	0.76 (0.64)	0.17 (0.78)	0.1676	374.1 (159.4)	322.6 (303.6)	0.0001
7 years	Whole population	39	0.57 (0.80)	0.06 (0.78)	0.3264	306.9 (147.0)	239.2 (271)	<0.0001
	BRVO	28	0.31 (0.45)	0.21 (0.49)	0.0154	298.5 (159.1)	221.8 (241.3)	<0.0001
	CRVO	11	1.23 (1.09)	−0.34 (1.19)	0.1824	334.8 (98.9)	297 (364.4)	0.0201
8 years	Whole population	19	0.48 (0.71)	0.2 (0.52)	0.0562	270.5 (155.0)	305.1 (305.2)	0.0001
	BRVO	16	0.30 (0.51)	0.23 (0.56)	0.0616	267.2 (163.5)	257.9 (246.2)	0.0002
	CRVO	3	1.40 (0.98)	0.03 (0.06)	0.2113	300.5 (0.71)	729.5 (581.9)	0.1635
Final visit	Whole population	223	0.69 (0.80)	0.11 (0.76)	0.0175	355.6 (171.9)	260.1 (292.7)	<0.0001
	BRVO	124	0.42 (0.57)	0.19 (0.60)	0.0003	316.0 (137.1)	220.9 (246.6)	<0.0001
	CRVO	99	1.02 (0.91)	0.01 (0.91)	0.4634	405.1 (197.2)	309.3 (336.8)	<0.0001