Automatic Quantification Software for Geographic Atrophy Associated with Age-Related Macular Degeneration: A Validation Study

Figure 2

The geographic atrophy (GA) analysis algorithm workflow consists of five steps: preprocessing of the data and layer segmentation results, generation of the integrated attenuation map, enhancement of the attenuation map, extraction of the GA region, and postprocessing of the results. The preprocessing step includes resegmentation of the outer segments/retinal pigment epithelium and Bruch’s membrane boundaries in each B-scan for better detection in typical GA patients and the disc mask generation in the X-Y plane from the input fovea and disc locations.