Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients

Table 3

Association of autoantibody levels with retinal vein occlusion in the German population-based Gutenberg Health Study (GHS), 2007–2012.

Autoantibody	Model 1		Model 2		Model 3
Log10-transformed autoantibody level (RVO: yes vs. no)	OR		OR		OR
Dermcidin	1.90 (0.89–4.09)	0.10	1.75 (0.79–3.88)	0.17	1.67 (0.75–3.72)	0.21
NFT3	2.44 (1.35–4.41)	0.003	2.64 (1.40–4.98)	0.003	2.49 (1.33–4.69)	0.005
SOD1	2.11 (1.21–3.68)	0.008	2.16 (1.21–3.85)	0.009	1.95 (1.08–3.51)	0.027
SRP14	2.65 (1.27–5.53)	0.009	2.70 (1.23–5.91)	0.013	2.79 (1.26–6.18)	0.011

Results are from conditional logistic regression analysis. Model 1 is adjusted for batch, model 2 is adjusted for age, sex, and cardiovascular risk factors (obesity, arterial hypertension, diabetes mellitus, smoking, dyslipidemia, family history of myocardial infarction or stroke, and batch), and model 3 is adjusted for age, sex, and cardiovascular risk factors (BMI, mean arterial blood pressure, HbA1c, HDL, LDL, triglycerides, smoking, family history of myocardial infarction or stroke, and batch). OR is the per log10-transformed autoantibody level.