Journal of Ophthalmology / 2020 / Article / Tab 2

Review Article

Use of iStent as a Standalone Operation in Patients with Open-Angle Glaucoma

Table 2

Success rate and complications of studies included in meta-analysis.

Author, yearNumber of eyes at baselineNumber of eyes at end pointSuccess rateComplication rate
IOP ≤18 mmHg (n, %)IOP reduction ≥20% (n, %)Event (n, %)Types of complication (%)

Buznego, 2008 [17]414141 (100)NR6 (15)Malposition (15)
Ahmed et al., 2014 [18]393939 (100)39 (100)0 (0)None
Fea et al., 2014 [19]949487 (92.6)89 (94.7)3 (3)IOP decompensation (1), one stent not visible (1), soreness/discomfort (1)
Voskanyan et al., 2014 [20]998871 (80.7)82 (93.2)35 (35.3)Elevated IOP (10.1), iStent obstruction (3), progression of cataract (1), allergic reaction to medications (1), iStent malposition (1), intraocular inflammation (1), subconjunctival hemorrhage (1), iStent not visible upon gonioscopy (13.1), posterior capsular opacification (2), goniosynechiae (1), lens-iris synechiae (1)
Donnenfeld et al., 2015 [21]392926 (89.7)25 (86.2)10 (25.6)Progression of cataract (7.7), death (5.1), hyphema (2.6), initial cataract (2.6), proliferative diabetic retinopathy (2.6), scar from age-related macular degeneration (2.6), cataract surgery (2.6)
Katz et al., 2015 [22]38 (1 device)3733 (89.2)33 (89.2)2 (5.3)Cataract surgery (5.3)
41 (2 devices)4137 (90.2)37 (90.2)0 (0)None
40 (3 devices)3835 (92.1)35 (92.1)2 (5.3)Cataract surgery (5.3)
Klamann et al., 2015 [23]17 (POAG)17NRNR32 (91.4)Intraoperative blood reflux (91.4)
15 (PEX)15NRNR
3 (PG)3NRNR
Ferguson et al., 2016 [24]4242NRNR1 (2.4)Elevated IOP (2.4)
Lindstrom et al., 2016 [25]575757 (100)43 (75.4)1 (1.8)Progression of cataract (1.8)
Vold et al., 2016 [26]543431 (91.1)NR12 (22.2)Progression of cataract (20.4), hyphema (1.8)
Berdahl et al., 2017 [27]535346 (86.8)48 (90.6)0 (0)None
Chang et al., 2017 [28]393530 (85.7)34 (97.1)13 (33.3)Transient hypotony (5.1), progression of cataract (23.1), insomnia/malaise (2.6), herpetic corneal ulcer (2.6)
Pahlitzsch et al., 2017 [29]2020NRNRNRNR
Shiba et al., 2017 [30]1084 (50)4 (50)9 (90)Hyphema (40), elevated IOP (10), peripheral anterior synechiae (40)
Katz et al., 2018 [31]38 (1 device)28NR17 (60.7)8 (21.1)Progression of cataract (21.1)
41 (2 devices)35NR32 (91.4)5 (12.2)Progression of cataract (12.2)
40 (3 devices)35NR32 (91.4)7 (17.5)Progression of cataract (17.5)
Ahmed et al., 2019 [32]777543 (57.3)10 (13.3)15 (19.5)Elevated IOP (5.2), new cataract (1.3), iStent obstruction (13.0)
Hengerer et al., 2019 [33]443332 (97.0)29 (87.9)4 (9.1)Mild hyphema (2.3), progression of cataract (4.5), uveitis (2.3)

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