Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center

Figure 1

Patients affected by PPS maculopathy (n = 4) compared to control patients taking PPS without known maculopathy (n = 93). Duration of PPS exposure, also when considered by body weight, was higher in affected patients compared to controls. The daily dose of PPS was higher in affected patients compared to controls (middle row, left). Cumulative PPS exposure, also when considered by body weight, was higher in affected patients compared to controls (bottom row). Box plots show median center line in box, 1st and 3rd quartile edge of boxes, and end of lines showing minimum and maximum. Dots outside of the bars represent outliers. X in the boxes represents the mean. values are results from two-tailed t-test. (a) . (b) . (c) . (d) . (e) . (f) .

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