In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Analysis of the Microcystic Keratitis

Figure 3

Confocal micrographs of the cornea. (a) IVCM micrograph of the superficial epithelium showing numerous small microcysts filled with highly reflective homogenous material (white arrow). Larger cysts filled with heterogenous hyporeflective and hyperreflective material (red arrows). (b) IVCM micrograph of the epithelium showing polymorphism along with disruption of a cytoarchitecture and disruption of the layered structure of the epithelium. Large cysts filled with heterogenous hyporeflective and hyperreflective material (red arrows). (c) IVCM image at the level of basal cells of corneal epithelium showing inflammatory changes. Brightly reflective and round structures visible at the centre of basal epithelial cells (red arrow). (d) IVCM micrograph of the Bowman layer showing increased density of Langerhans cells (white arrow) and activated keratocytes in the anterior stroma. Corneal nerve with normal morphology (red arrow). (e) IVCM image at the level of intermediate stroma showing activated keratocytes. (f) IVCM image of the endothelium with normal structure.