Research Article

The Therapeutic Effect of Combination of Orbital Decompression Surgery and Methylprednisolone Pulse Therapy on Patients with Bilateral Dysthyroid Optic Neuropathy

Table 2

Clinical characteristics of the operated eyes and fellow eyes in patients with bilateral DON before and after treatment.

Operated eye, N = 23Fellow eye, N = 23
Before treatmentAfter treatmentBefore treatmentAfter treatment

BCVA1.3 ± 0.630.7 ± 0.540.0010.7 ± 0.510.5 ± 0.430.018
IOP (mmHg)20.5 ± 6.2116.1 ± 4.430.00218.5 ± 4.8018.5 ± 7.240.993
Proptosis (mm)20.0 ± 4.2415.7 ± 3.00<0.00119.2 ± 4.1817.8 ± 3.840.008
Upper eyelid retraction (mm)3.1 ± 2.051.9 ± 1.46<0.0013.0 ± 2.122.4 ± 1.76<0.001
CAS1.6 ± 1.370.8 ± 0.870.0111.5 ± 1.370.6 ± 0.730.005

Wilcoxon matched-pairs signed ranks sum test between the eyes before and after treatment. Paired t-test between the eyes before and after treatment. DON: dysthyroid optic neuropathy; BCVA: best-corrected visual acuity; IOP: intraocular pressure; CAS: clinical activity score.