Research Article

The Therapeutic Effect of Combination of Orbital Decompression Surgery and Methylprednisolone Pulse Therapy on Patients with Bilateral Dysthyroid Optic Neuropathy

Table 3

Improvement of clinical parameters of the operated eyes and fellow eyes after treatment in patients with bilateral DON.

Improvement of operated eye, N = 23Improvement of fellow eye, N = 23

BCVA0.5 ± 0.590.2 ± 0.340.046
IOP (mmHg)4.4 ± 6.790.0 ± 5.710.021
Proptosis (mm)4.3 ± 2.521.4 ± 1.94<0.001
Upper eyelid retraction (mm)1.3 ± 1.120.6 ± 0.670.003
CAS0.8 ± 1.370.9 ± 1.280.771

Wilcoxon matched-pairs signed ranks sum test between the eyes before and after treatment. Paired t-test between the eyes before and after treatment. DON: dysthyroid optic neuropathy; BCVA: best corrected visual acuity; IOP: intraocular pressure; CAS: clinical activity score.