The Therapeutic Effect of Combination of Orbital Decompression Surgery and Methylprednisolone Pulse Therapy on Patients with Bilateral Dysthyroid Optic Neuropathy
Table 6
Visual evoked potential parameters of the operated eyes and fellow eyes in patients with bilateral DON before and after treatment.
Operated eye, N = 23
Fellow eye, N = 23
Before treatment
After treatment
Before treatment
After treatment
60′ P100 latency (ms)
166.3 ± 38.98
138.2 ± 37.08
0.002
137.8 ± 39.00
141.1 ± 36.36
0.139
60′ P100 amplitude (μV)
3.8 ± 3.58
6.3 ± 4.05
0.002
7.7 ± 4.39
7.3 ± 6.19
0.278
30′ P100 latency (ms)
186.2 ± 26.84
145.9 ± 33.82
0.001
146.7 ± 32.66
163.9 ± 41.98
0.139
30′ P100 amplitude (μV)
2.1 ± 3.16
4.5 ± 3.51
0.001
5.1 ± 3.22
5.3 ± 4.84
0.926
15′ P100 latency (ms)
187.5 ± 25.19
166.8 ± 31.55
0.005
160.2 ± 33.48
170.1 ± 36.10
0.307
15′ P100 amplitude (μV)
2.1 ± 3.53
4.2 ± 4.97
0.021
5.4 ± 4.40
4.3 ± 4.18
0.172
Wilcoxon matched-pairs signed ranks sum test between the eyes before and after treatment. DON: dysthyroid optic neuropathy.
