Research Article

Corneal Cross-Linking as Treatment in Pediatric Keratoconus: Comparison of Two Protocols

Table 2

Intergroup comparison of the delta in outcomes at 6 and 12 months after the procedure.

Variable, mean ± SDA-CXLS-CXL valueA-CXLS-CXL value
Delta after 6 monthsDelta after 12 months

UCDVA (logMAR)−0.1 ± 0.7−0.3 ± 0.70.660.1 ± 0.5−0.6 ± 0.80.03
BCDVA (logMAR)−0.05 ± 0.3−0.1 ± 0.30.79−0.1 ± 0.3−0.2 ± 0.20.77
EDC (cells/mm2)−18.0 ± 70.0−21.4 ± 560.48−22.3 ± 11.7−28.0 ± 9.00.34
Kmax (D)0.4 ± 2.3−0.3 ± 1.30.400.2 ± 2.1−0.7 ± 2.30.20
K1flat front (D)−0.4 ± 0.60.2 ± 0.80.03−0.1 ± 0.90.4 ± 1.90.29
K2steep front (D)−0.3 ± 1.00.2 ± 1.10.21−0.1 ± 1.3−0.1 ± 1.00.95
Kmean front (D)0.2 ± 0.8−0.4 ± 0.80.07−0.1 ± 10.2 ± 1.50.49
Astigmatism front (D)−0.1 ± 1.20.1 ± 0.50.61−0.04 ± 1.2−0.2 ± 0.70.79

Astigmatism back (D)−0.1 ± 0.2−0.1 ± 0.20.12−0.1 ± 0.20.7 ± 1.70.26
Pachymetry center (μm)−7.8 ± 22.2−16.6 ± 16.40.29−7.1 ± 18.6−3.4 ± 42.50.80
Pachymetry thinnest point (μm)−9.8 ± 23.3−11.0 ± 21.30.90−11.8 ± 14.6−29.8 ± 30.20.12

SD: standard deviation; delta: value after operation–value before operation; D: diopter; UCDVA: uncorrected distance visual acuity; BCDVA: best corrected distance visual acuity; K: keratometry; EDC: endothelial density count.