Corneal Cross-Linking as Treatment in Pediatric Keratoconus: Comparison of Two Protocols
Table 3
Intragroup comparison of preoperative and 6-month and 12-month postoperative clinical parameters.
Variables
A-CXL
S-CXL
Baseline mean ± SD
6-month mean ± SD
value
12-month mean ± SD
value
Baseline mean ± SD
6 months mean ± SD
value
12 months mean ± SD
value
UCDVA (logMAR)
0.7 ± 0.5
0.6 ± 0.5
0.42
0.6 ± 0.5
0.51
0.9 ± 0.6
0.6 ± 0.6
0.40
0.3 ± 0.3
0.11
BCDVA (logMAR)
0.4 ± 0.2
0.4 ± 0.2
0.43
0.3 ± 0.2
0.04
0.4 ± 0.2
0.4 ± 0.3
0.54
0.4 ± 0.5
0.11
EDC (cells/mm2)
2786.3 ± 172.6
2766.8 + 201.8
0.25
2764.0 + 149.5
0.15
2734.0 ± 171.1
2711 ± 196.3
0.49
2706.3 + 128.4
0.24
Kmax (D)
55.2 ± 4.9
55.4 ± 6.0
0.34
55.4 + 5.3
0.57
54.5 ± 5.5
54.1 ± 4.0
0.58
53.7 + 4.8
0.30
K1flat front (D)
46.9 ± 3.1
46.9 ± 3.4
0.15
47.2 + 3.3
0.94
45.9 ± 4.1
45.3 ± 3.0
0.08
45.8 + 4.4
0.47
K2steep front (D)
51.0 ± 3.4
46.9 ± 3.4
0.41
51.5 + 3.3
0.76
49.8 ± 4.7
45.3 ± 3.0
0.31
48.9 + 5.1
0.76
Kmean front (D)
48.9 ± 3.2
48.7 ± 3.6
0.24
49.3 + 3.2
0.63
47.8 ± 4.3
47.4 ± 3.1
0.16
47.7 + 4.6
0.69
Astigmatism front (D)
4.2 ± 1.8
3.8 ± 1.7
0.65
4.3 + 2.1
0.86
3.7 ± 1.9
4.4 ± 1.5
0.55
2.7 + 1.3
0.53
Astigmatism back (D)
1.0 ± 0.4
0.9 ± 0.4
0.04
0.9 + 0.4
0.07
0.8 ± 0.4
1.0 ± 0.3
0.43
1.4 + 1.4
0.31
Pachymetry center (μm)
464.7 ± 31.5
462.6 ± 30.4
0.09
457.9 + 42
0.05
477.1 ± 45.2
465.8 ± 47.7
0.02
471.2 + 70.1
0.81
Pachymetry thinnest point (μm)
460.5 ± 41.1
444.6 ± 33.2
0.05
444.7 + 36.6
<.001
454.5 ± 46.1
448.0 ± 33.2
0.16
433.8 + 47.7
0.02
SD: standard deviation; D: diopter; UCDVA: uncorrected distance visual acuity; BCDVA: best corrected distance visual acuity; K: keratometry; EDC: endothelial density count. P values < 0.05 are considered significant.
