Research Article
Symptoms of Dry Eye Disease in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19)
Table 3
The clinical characteristics of COVID-19 patients with subtype DED symptoms score groups.
| | Characteristic | No.(%) | | OSDI score | DEQ-5 score | | NO DED (n = 14, 33.33%) | Mild DED (n = 5, 11.90%) | Moderate DED (n = 16, 38.10%) | Severe DED (n = 7, 16.67%) | value | NO DED (n = 16, 38.10%) | DED (n = 26, 61.9%) | value |
| | Age (SD), years | 57.50 (14.60) | 49.60 (6.80) | 54.50 (11.91) | 60.60 (8.33) | 0.88 | 54.12 (13.57) | 56.89 (11.04) | 0.748 | | Age,y | | | | | | | | | | <50 | 4 (28.57) | 3 (60.00) | 7 (43.75) | 1 (14.29) | 0.34 | 7 (43.75) | 8 (30.77) | 0.60 | | ≥50 | 10 (71.43) | 2 (40.00) | 9 (56.25) | 6 (85.71) | | 9 (56.25) | 18 (69.23) | | | Gender | | | | | | | | | | Male | 5 (35.71) | 1 (20.00) | 10 (62.55) | 1 (14.29) | 0.11 | 8 (50.00) | 9 (34.62) | 0.51 | | Female | 9 (64.29) | 4 (80.00) | 6 (37.50) | 6 (85.71) | | 8 (50.00) | 17 (65.38) | | | Hospitalization (SD),days | 28.21 (6.59) | 31.20 (2.39) | 31.19 (8.02) | 30.71 (9.69) | 0.33 | 28.69 (6.84) | 31.00 (7.58) | 0.33 | | Previous history | | | | | | | | | | Hypertension | 7 (50.00) | 1 (20.00) | 4 (25.00) | 4 (57.14) | 0.33 | 5 (31.25) | 11 (42.31) | 0.70 | | Diabetes | 3 (21.42) | 2 (40.00) | 1 (6.25) | 1 (14.29) | 0.27 | 5 (31.25) | 2 (7.69) | 0.09 | | Cardiac or stroke disease | 0 (0.00) | 1 (20.00) | 0 (0.00) | 2 (28.57) | 0.02 | 0 (0.00) | 3 (11.54) | 0.28 | | Thyroid disease | 1 (7.14) | 1 (20.00) | 0 (0.00) | 0 (0.00) | 0.16 | 1 (6.25) | 1 (3.85) | 1.00 | | Kidney disease | 1 (7.14) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0.62 | | | | | Digestive system disease | 2 (14.29) | 1 (20.00) | 3 (18.75) | 1 (14.29) | 1.00 | 2 (12.50) | 5 (19.23) | 0.69 | | Respiratory system diseases | 0 (0.00) | 1 (20.00) | 3 (18.75) | 1 (14.29) | 0.28 | 0 (0.00) | 5 (19.23) | 0.14 | | History of eye diseases | | | | | | | | | | Glaucoma | 0 (0.00) | 1 (20.00) | 0 (0.00) | 1 (14.29) | 0.14 | 0 (0.00) | 2 (7.69) | 0.52 | | Cataract | 0 (0.00) | 1 (20.00) | 1 (6.25) | 1 (14.29) | 0.41 | 0 (0.00) | 3 (11.54) | 0.28 | | Myopia | 2 (14.29) | 2 (40.00) | 2 (12.50) | 2 (28.57) | 0.41 | 2 (12.50) | 6 (23.08) | 0.69 | | Ocular fundus disease | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (14.29) | 0.16 | 0 (0.00) | 1 (3.85) | 1.00 | | Ophthalmic medication (within one month) | 2 (14.29) | 2 (40.00) | 2 (12.50) | 2 (28.57) | 0.48 | 2 (12.50) | 6 (23.08) | 0.69 | | Activity of ocular disease (within three months) | 0 (0.00) | 1 (20.00) | 0 (0.00) | 1 (14.29) | 0.14 | 0 (0.00) | 2 (7.69) | 0.52 | | Ocular operation or trauma (within three months) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (14.29) | 0.16 | 0 (0.00) | 1 (3.85) | 1.00 | | Typical symptoms | | | | | | | | | | Fever | 9 (64.29) | 5 (100.00) | 13 (81.25) | 6 (85.71) | 0.43 | 11 (68.75) | 22 (84.62) | 0.27 | | Cough | 9 (64.29) | 5 (100.00) | 11 (68.75) | 3 (42.86) | 0.26 | 12 (75%) | 16 (61.54) | 0.51 | | Pharyngodynia | 4 (28.57) | 0 (0.00) | 2 (12.50) | 0 (0.00) | 0.33 | 4 (25%) | 2 (7.69) | 0.18 | | Anhelation | 6 (42.86) | 1 (20.00) | 6 (37.50) | 1 (14.29) | 0.61 | 5 (31.25%) | 9 (34.62) | 1.00 | | Fatigue | 6 (42.86) | 2 (40.00) | 4 (25.00) | 4 (57.14) | 0.48 | 6 (37.5%) | 10 (38.46) | 1.00 | | Muscle soreness | 1 (7.14) | 3 (60.00) | 4 (25.00) | 4 (57.14) | 0.03 | 2 (1.25%) | 10 (38.46) | 0.09 | | Bosom frowsty and (or) ache | 2 (14.29) | 0 (0.00) | 2 (12.50) | 2 (28.57) | 0.56 | 1 (6.25%) | 5 (19.23) | 0.38 | | Abdominal pain, diarrhea | 1 (7.14) | 0 (0.00) | 3 (18.75) | 1 (14.29) | 0.84 | 1 (6.25%) | 4 (15.38) | 0.63 |
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