Corneal and Epithelial Thickness Mapping: Comparison of Enhanced Spectral-Domain- and Spectral-Domain-Optical Coherence Tomography
Table 1
Interobserver reproducibility of corneal epithelial thickness assessment with Enhanced Spectral-Domain and Spectral-Domain-Optical Coherence Tomography in normal eyes.
Mean standard deviation (μm)
Mean coefficient of variation (%)
ESD-OCT
SD-OCT
ESD-OCT
SD-OCT
Central
0.88
0.73
0.34
1.7
1.3
0.24
Minimal
1.18
1.17
0.98
2.4
2.4
0.97
Maximal
1.06
1.032
0.89
1.8
1.8
0.96
2–5 mm superior
1.79
0.87
0.001
3.4
1.6
0.0006
2–5 mm supero-nasal
1.59
0.76
0.0004
3.0
1.4
0.0002
2–5 mm nasal
1.46
0.82
0.002
2.7
1.5
0.001
2–5 mm infero-nasal
1.14
0.75
0.02
2.1
1.4
0.01
2–5 mm inferior
1.36
0.77
0.002
2.5
1.4
0.001
2–5 mm infero-temporal
1.36
0.69
0.002
2.5
1.3
0.001
2–5 mm temporal
1.44
0.70
0.0001
2.8
1.3
0.00005
2–5 mm supero-temporal
1.67
0.93
0.005
3.2
1.8
0.003
5–6 mm superior
2.82
1.06
0.002
5.7
2.1
0.002
5–6 mm supero-nasal
2.16
0.93
0.000007
4.1
1.8
0.000004
5–6 mm nasal
1.43
0.87
0.001
2.6
1.6
0.002
5–6 mm infero-nasal
1.66
0.86
0.003
3.0
1.6
0.004
5–6 mm inferior
1.46
0.75
0.002
2.6
1.4
0.002
5–6 mm infero-temporal
1.56
0.83
0.003
2.8
1.6
0.006
5–6 mm temporal
1.88
0.91
0.0006
3.6
1.7
0.0009
5–6 mm supero-temporal
1.79
1.22
0.045
3.5
2.4
0.045
Each measurement was performed by 3 trained operators in 30 eyes of 30 patients. Data in bold indicate significant differences between ESD-OCT and SD-OCT.
