Novel Likely Pathogenic Variants Identified by Panel-Based Exome Sequencing in Congenital Cataract Patients

Table 2

Summary of probands sequencing data in three families.

Samples	Proband (family A)	Proband (family B)	Proband (family C)
Raw_data_bases (Mb)	2726.51	2825.35	1443.22
Clean_data_bases (Mb)	2615.89	2630.75	1393.44
Aligned_bases (Mb)	2597.73	2618.71	1387.15
Aligned (%)	99.31	99.54	99.55
Initial bases on target	456294	456294	455256
Base covered on target	453517	453355	451520
Coverage of target region (%)	99.39	99.36	99.18
Effective bases on target	177513627	189678089	127259738
Fraction of effective bases on target (%)	6.83	7.24	9.17
Average sequencing depth on target	389.03	415.69	279.53
Fraction of target covered with at least 4X (%)	99.16	99.09	98.73
Fraction of target covered with at least 10X (%)	98.95	98.78	97.89
Fraction of target covered with at least 20X (%)	98.28	98.01	95.63
Duplication rate (%)	22.72	24.99	28.34