Incorporating Differential Gene Expression Analysis with Predictive Biomarkers to Identify Novel Therapeutic Drugs for Fuchs Endothelial Corneal Dystrophy

Figure 6

L1000CDS² identify drug candidates that reverse the differential expression signatures. A bar chart showing the top small molecules found by the L1000CDS² query is contained in the figure. The left panel shows the small molecules that imitate the signature of gene expression observed, while the small molecules that reverse it are seen on the right panel.

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