Journal of Ophthalmology

Research Article

Changes in Intraocular Pressure after Transepithelial Photorefractive Keratectomy and Femtosecond Laser In Situ Keratomileusis

Table 3

Potential factors affecting the changes in IOP after FS-LASIK and TPRK were analyzed with marginal linear regression models using the GEE.


	Univariate			value	Multivariate			value
	B	SE	95% CI	value	B	SE	95% CI	value

Group
LASIK	Ref.				Ref.
PRK	2.49	(0.40)	(1.71, 3.27)	<0.001	1.75	(0.49)	(0.79, 2.70)	<0.001
Gender
Male	Ref.
Female	−0.17	(0.53)	(−1.22, 0.87)	0.745
Age (year)	−0.02	(0.03)	(−0.07, 0.04)	0.590
SE (D)	0.24	(0.09)	(0.06, 0.43)	0.009
Average K (D)	0.01	(0.20)	(−0.38, 0.40)	0.957
Depth of ablation (μm)	−0.03	(0.01)	(−0.04, −0.02)	<0.001	−0.02	(0.01)	(−0.03, −0.01)	0.004
IOP preop	−0.69	(0.08)	(−0.84, −0.54)	<0.001
CCT (μm)	−0.01	(0.01)	(−0.03, 0.00)	0.122
A1L (mm)	−0.55	(0.51)	(−1.55, 0.45)	0.279
A1V (m/s)	28.61	(8.69)	(11.58, 45.64)	0.001	−5.57	(11.05)	(−27.23, 16.10)	0.615
A2L (mm)	−0.68	(0.38)	(−1.42, 0.06)	0.071
A2V (m/s)	−13.29	(8.68)	(−30.30, 3.72)	0.126
A1T (ms)	−4.79	(0.52)	(−5.82, −3.76)	<0.001
A2T (ms)	2.11	(0.56)	(1.01, 3.20)	<0.001
Radius (mm)	−0.07	(0.17)	(−0.39, 0.26)	0.697
PD (mm)	3.80	(0.74)	(2.35, 5.25)	<0.001	2.79	(0.84)	(1.15, 4.44)	<0.001
DA (mm)	9.89	(1.73)	(6.50, 13.27)	<0.001
Young’s modulus
(MPa)	0.15	(0.21)	(−0.26, 0.56)	0.462
CBI	1.10	(0.41)	(0.29, 1.91)	0.008	0.15	(0.39)	(−0.62, 0.92)	0.706
DA ratio	0.71	(0.45)	(−0.17, 1.59)	0.112
Integr. radius (mm⁻¹)	0.53	(0.18)	(0.18, 0.88)	0.003	0.09	(0.23)	(−0.37, 0.55)	0.692
ARTh	0.00	(0.00)	(−0.00, 0.00)	0.299
SP-A1	−0.04	(0.02)	(−0.08, −0.01)	0.015

∆IOP = −16.47 + 1.75 (PRK) − 5.57 (A1V) + 2.79 (peak distance) + 0.15 (CBI) + 0.09 (Integr. radius) − 0.02 (ablation depth). GEE, generalized estimating equation. and . FS-LASIK, femtosecond laser in situ keratomileusis; TPRK, transepithelial photorefractive keratectomy; SE, spherical equivalent; K, keratometric readings in diopter; IOP, intraocular pressure; bIOP, biomechanically corrected IOP; A1L, first applanation length; A1V, applanation-1 velocity; A2L, second applanation length; A2V, applanation-2 velocity; PD, peak distance; DA, deformation amplitude; CCT, central corneal thickness; A1T, applanation-1 time; A2T, applanation-2 time; CBI, Corvis Biomechanical Index; DA ratio, DA ratio at 2.0 mm; Integr. radius, the integrated area under the radius of the inversed curvature during the concave phase; ARTh, Ambrósio’s relational thickness in the horizontal profile; SP-A1, stiffness parameter at applanation 1.