Journal of Ophthalmology

Research Article

Changes in Intraocular Pressure after Transepithelial Photorefractive Keratectomy and Femtosecond Laser In Situ Keratomileusis

Table 4

Potential factors affecting the changes in bIOP after FS-LASIK and TPRK were analyzed with marginal linear regression models using the GEE.


	Univariate			value	Multivariate			value
	B	SE	95% CI	value	B	SE	95% CI	value

Group
LASIK	Ref.				Ref.
PRK	1.85	(0.37)	(1.13, 2.57)	<0.001	1.64	(0.47)	(0.72, 2.57)	0.001
Gender
Male	Ref.
Female	−0.42	(0.47)	(−1.35, 0.50)	0.370
Age (year)	−0.02	(0.02)	(−0.07, 0.03)	0.371
SE (D)	0.07	(0.09)	(−0.10, 0.24)	0.409
Average K (D)	0.01	(0.17)	(−0.33, 0.35)	0.950
Depth of ablation (μm)	−0.01	(0.01)	(−0.02, 0.00)	<0.109	0.002	(0.01)	(−0.01, 0.01)	0.702
bIOP preop (mmHg)	−0.63	(0.10)	(−0.83, −0.43)	<0.001
CCT (μm)	0.00	(0.01)	(−0.01, 0.02)	0.727
A1L (mm)	−0.27	(0.48)	(−1.21, 0.66)	0.567
A1V (m/s)	18.54	(7.99)	(2.87, 34.21)	0.020	−4.20	(10.60)	(−24.97, 16.57)	0.692
A2L (mm)	−0.63	(0.34)	(−1.30, 0.03)	0.061
A2V (m/s)	−11.02	(7.87)	(−26.44, 4.40)	0.161
A1T (ms)	−3.59	(0.52)	(−4.61, −2.57)	<0.001
A2T (ms)	1.63	(0.52)	(0.61, 2.65)	<0.002
Radius (mm)	−0.02	(0.14)	(−0.30, 0.26)	0.876
PD (mm)	2.96	(0.69)	(1.61, 4.32)	<0.001	2.35	(0.81)	(0.77, 3.94)	0.004
DA (mm)	7.61	(1.60)	(4.47, 10.76)	<0.001
Young’s modulus (MPa)	0.13	(0.18)	(−0.23, 0.49)	0.469
CBI	0.69	(0.35)	(0.00, 1.38)	0.050	0.09	(0.35)	(−0.60, 0.78)	0.798
DA ratio	0.42	(0.31)	(−0.18, 1.02)	0.167
Integr. radius (mm⁻¹)	0.32	(0.15)	(0.03, 0.61)	0.029	0.001	(0.22)	(−0.43, 0.43)	0.997
ARTh	0.00	(0.00)	(−0.00, 0.00)	0.699
SP-A1	−0.02	(0.02)	(−0.05, 0.01)	0.169

∆bIOP = −13.39 + 1.64 (PRK) − 4.20 (A1V) + 2.35 (peak distance) + 0.09 (CBI) + 0.001 (Integr. radius) + 0.002 (ablation depth). GEE, generalized estimating equation. and . FS-LASIK, femtosecond laser in situ keratomileusis; TPRK, transepithelial photorefractive keratectomy; SE, spherical equivalent; K, keratometric readings in diopter; IOP, intraocular pressure; bIOP, biomechanically corrected IOP; A1L, first applanation length; A1V, applanation-1 velocity; A2L, second applanation length; A2V, applanation-2 velocity; PD, peak distance; DA, deformation amplitude; CCT, central corneal thickness; A1T, applanation-1 time; A2T, applanation-2 time; CBI, Corvis Biomechanical Index; DA ratio, DA ratio at 2.0 mm; Integr. radius, the integrated area under the radius of the inversed curvature during the concave phase; ARTh, Ambrósio’s relational thickness in the horizontal profile; SP-A1, stiffness parameter at applanation 1.