Time Course of Lens Epithelial Cell Behavior in Rabbit Eyes following Lens Extraction and Implantation of Intraocular Lens

Figure 5

Immunolocalization of α-SMA in pseudophakic rabbit eyes 1 month after cataract surgery. (a) The capsular bag is filled with lens fibers. Differentiated LECs are also present between the anterior surface of the IOL optic and the anterior capsule. Some of these lens fibers migrated beyond the anterior capsule margin and formed posterior synechia to the iris (arrow). The lens fibers migrated onto the posterior capsule from the periphery to the center (arrowhead), which showed no LECs. Bar = 800 μm. (b) Higher power view of LECs around the margin of the anterior capsule (arrow). The arrowhead indicates the posterior synechia of the lens fibers to the iris. Bar = 250 μm. (c) Higher power view of lens fibers on the central posterior capsule. Differentiated LECs, which form the Elschnig pearls type of opacification, are present over the α-SMA-positive LECs attached to the wrinkled posterior capsule (arrows). Bar = 250 μm. (a–c) Sections were stained with 3-3’-diaminobenzidine hydrochloride and counterstained with hematoxylin. The asterisks indicate the IOL optic.

(a)

(b)

(c)