Research Article
Comparison of Standard and Transepithelial Corneal Cross-Linking for the Treatment of Keratoconus: A Meta-analysis
Table 2
Risk of bias assessment based on the Newcastle-Ottawa Scale for nonrandomized studies.
| Item | Akbar et al. | Jouve et al. | Kocak et al. | Madeira et al. | Vinciguerra et al. |
| Selection | Representativeness of the exposed cohort | 1 | 1 | 1 | 1 | 1 | Selection of the nonexposed cohort | 1 | 1 | 1 | 1 | 1 | Ascertainment of exposure to implants | 1 | 1 | 1 | 1 | 1 | Demonstration that the outcome of interest was not present at the start of the study | 0 | 1 | 0 | 0 | 1 |
| Comparability | Comparability of cohorts on the basis of the design or analysis | 1 | 2 | 2 | 2 | 1 |
| Outcome | Ascertainment of outcome | 1 | 1 | 1 | 1 | 1 | Followed up long enough for outcome to occur | 1 | 1 | 1 | 1 | 1 | Adequacy of follow-up of cohort | 1 | 1 | 1 | 1 | 1 |
| Total score | 7 | 9 | 8 | 8 | 8 |
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