Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway

Figure 4

. Intravitreal injection of PFD does not cause apoptosis. TUNEL (green) and DAPI (blue) immunofluorescence staining of mouse choroid/RPE/retina cryosections from the normal: PBS and 0.5% PFD groups (IPL: inner plexiform layer; INL: inner nuclear layer; OPL: outer plexiform layer; ONL: outer nuclear layer; IS: inner segment; OS: outer segment). Scale bar: 200 μm.