Research Article
Preliminary Characterization of Predictive Factors of the Visual Change after Epi-On and Epi-Off Corneal Collagen Crosslinking Techniques
Table 3
Differences between the epi-on and epi-off groups in the corneal tomographic parameters in the different visits of the follow-up.
| | Mean (SD) | Preoperative | -value | Postoperative 3 months | - value | Postoperative 12 months | - value | | Median (Range) | Epi-on | Epi-off | Epi-on | Epi-off | Epi-on | Epi-off |
| | Anterior K1 (D) | 46.90 (3.93) | 45.02 (3.22) | 0.038 | 47.20 (3.81) | 45.05 (3.34) | 0.021 | 47.07 (4.20) | 44.75 (3.52) | 0.027 | | | 47.50 (14.70) | 44.40 (12.80) | | 47.70 (13.50) | 44.60 (12.10) | | 47.55 (16.60) | 44.20 (12.40) | | | Anterior K2 (D) | 51.93 (4.87) | 49.52 (4.18) | 0.035 | 51.71 (4.68) | 49.15 (4.07) | 0.024 | 51.88 (5.36) | 48.89 (4.34) | 0.021 | | | 52.25 (19.80) | 49.25 (18.30) | | 52.70 (19.30) | 49.25 (17.30) | | 52.01 (20.10) | 48.60 (17.80) | | | Posterior K1 (D) | −6.94 (0.83) | −6.55 (0.72) | 0.048 | −6.90 (0.77) | −6.61 (0.73) | 0.137 | −6.91 (0.83) | −6.60 (0.71) | 0.129 | | | −6.85 (3.30) | −6.50 (2.70) | | −7.00 (2.60) | −6.55 (2.90) | | −7.00 (3.60) | −6.50 (2.90) | | | Posterior K2 (D) | −7.92 (1.00) | −7.53 (0.84) | 0.092 | −7.95 (0.98) | −7.50 (0.84) | 0.054 | −7.86 (1.02) | −6.75 (3.14) | 0.085 | | | −7.90 (3.80) | −7.55 (3.60) | | −8.00 (3.90) | −7.45 (3.60) | | −7.95 (3.90) | −7.50 (17.20) | | | K-max (D) | 60.31 (6.47) | 56.54 (6.35) | 0.020 | 59.90 (6.24) | 56.15 (6.27) | 0.028 | 59.88 (7.19) | 55.49 (6.62) | 0.018 | | | 59.50 (26.50) | 55.60 (23.40) | | 60.35 (25.70) | 55.75 (23.30) | | 59.85 (28.50) | 54.30 (25.30) | | | D index | 11.26 (4.09) | 8.31 (3.36) | 0.002 | 11.54 (4.09) | 8.38 (3.18) | 0.001 | 10.96 (4.55) | 8.23 (3.32) | 0.011 | | | 11.49 (16.53) | 7.82 (13.52) | | 11.81 (15.67) | 8.53 (14.35) | | 11.44 (16.85) | 8.39 (13.97) | | | CCT (μm) | 455.64 (36.47) | 484.34 (42.16) | 0.004 | 460.58 (38.34) | 485.09 (41.67) | 0.015 | 458.78 (35.88) | 488.54 (40.02) | 0.004 | | | 454.38 (135.00) | 476.0 (157.00) | | 447.00 (142.00) | 476.00 (155.00) | | 460.00 (140.00) | 477.00 (149.00) | | | ACT (μm) | 442.47 (38.91) | 477.03 (41.89) | 0.001 | 446.00 (39.79) | 478.59 (42.17) | 0.002 | 447.00 (36.59) | 480.64 (42.05) | 0.003 | | | 436.00 (135.00) | 468.00 (158.00) | | 435.00 (129.00) | 469.00 (167.00) | | 443.50 (132.00) | 469.00 (145.00) | | | MCT (μm) | 428.70 (35.36) | 467.09 (41.08) | <0.001 | 430.61(37.08) | 468.75(42.58) | 0.001 | 433.07 (35.02) | 470.19 (42.46) | 0.001 | | | 419.50 (141.0) | 461.0 (157.0) | | 425.0(158) | 461.0(170) | | 428.50 (126.0) | 463.0 (145.0) | | | Corneal volume (mm3) | 55.62 (3.47) | 57.21 (4.11) | 0.094 | 56.14 (3.63) | 57.70 (4.09) | 0.114 | 56.01 (3.75) | 58.16 (4.23) | 0.044 | | | 55.65 (16.40) | 57.90 (16.60) | | 56.40 (17.40) | 59.00 (16.00) | | 56.30 (16.60) | 59.10 (16.70) | | | Q-val | −0.94 (0.53) | −0.78 (0.43) | 0.187 | −0.94 (0.55) | −0.77 (0.46) | 0.192 | −0.91 (0.51) | −0.69 (0.41) | 0.064 | | | −0.85 (2.52) | −0.80 (1.62) | | −0.99 (2.26) | −0.73 (2.02) | | −0.97 (1.98) | −0.68 (1.47) | |
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K1, flattest keratometry; K2, steepest keratometry; K-max, maximum keratometry; D, total deviation value; CCT, central corneal thickness; ACT, apex corneal thickness; Q-val, asphericity of the anterior corneal surface; MCT: minimal corneal thickness.
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