Research Article
Preliminary Characterization of Predictive Factors of the Visual Change after Epi-On and Epi-Off Corneal Collagen Crosslinking Techniques
Table 5
Differences between epi-on and epi-off groups in corneal topometric parameters in the different visits of the follow-up.
| Mean (SD) | Preoperative | - value | Postoperative 3 months | - value | Postoperative 12 months | - value | Median (Range) | Epi-on | Epi-off | Epi-on | Epi-off | Epi-on | Epi-off |
| Anterior total RMS (μm) | 15.84 (5.35) | 12.93 (6.10) | 0.013 | 15.63 (5.38) | 12.30 (5.73) | 0.018 | 15.00 (6.19) | 11.71 (6.14) | 0.045 | | 15.14 (22.97) | 12.33 (28.58) | | 15.01 (22.33) | 12.09 (26.45) | | 13.71 (23.21) | 11.44 (28.01) | | Anterior HOA RMS (μm) | 4.06 (1.43) | 3.32 (1.68) | 0.042 | 4.04 (1.50) | 3.14 (1.45) | 0.022 | 3.84 (1.63) | 3.01 (1.52) | 0.048 | | 4.03 (6.14) | 3.09 (8.39) | | 4.12 (5.99) | 3.05 (7.17) | | 3.40 (5.75) | 3.00 (7.64) | | Anterior LOA RMS (μm) | 15.30 (5.19) | 12.49 (5.89) | 0.014 | 15.09 (5.19) | 11.88 (5.57) | 0.019 | 14.49 (5.99) | 11.34 (5.98) | 0.048 | | 14.84 (22.26) | 11.91 (27.33) | | 14.50 (21.64) | 11.72 (25.47) | | 13.36 (22.82) | 11.01 (27.02) | | Anterior (μm) | −3.14 (1.68) | −2.51 (1.75) | 0.075 | −3.08 (1.67) | −2.48 (1.63) | 0.125 | −2.93 (1.78) | −2.36 (1.67) | 0.239 | | −3.38 (7.03) | −2.55 (8.82) | | −3.16 (7.03) | −2.62 (8.31) | | −2.63 (6.14) | −2.60 (8.60) | | Anterior Z31 (μm) | −0.07 (1.49) | 0.08 (0.87) | 0.397 | −0.13 (1.57) | 0.04 (0.82) | 0.398 | 0.00 (1.51) | 0.02 (0.83) | 0.861 | | −0.36 (5.38) | 0.13 (3.96) | | −0.42 (7.08) | 0.13 (3.49) | | −0.30 (5.32) | 0.08 (3.36) | | Anterior (μm) | −0.86 (0.99) | −0.47 (0.92) | 0.116 | −0.88 (0.95) | −0.56 (0.84) | 0.189 | −0.85 (1.00) | −0.45 (0.87) | 0.131 | | −0.79 (4.34) | −0.28 (3.33) | | −0.97 (3.74) | −0.49 (2.95) | | −0.81 (3.94) | −0.16 (3.29) | | Posterior total RMS (μm) | 3.66 (1.19) | 2.87 (1.32) | 0.010 | 3.61 (1.33) | 2.86 (1.16) | 0.024 | 3.45 (1.52) | 3.17 (2.75) | 0.816 | | 3.48 (4.70) | 2.83 (5.94) | | 3.09 (4.75) | 2.79 (5.54) | | 2.94 (6.34) | 2.60 (15.40) | | Posterior HOA RMS (μm) | 0.77 (0.48) | 0.64 (0.34) | 0.162 | 1.08 (0.37) | 0.81 (0.32) | 0.005 | 1.04 (0.45) | 0.88 (0.67) | 0.048 | | 0.76 (0.83) | 0.47 (1.11) | | 0.94 (1.54) | 0.79 (1.62) | | 0.89 (1.70) | 0.73 (3.70) | | Posterior LOA RMS (μm) | 3.49 (1.15) | 2.74 (1.27) | 0.013 | 3.44 (1.28) | 2.74 (1.12) | 0.044 | 3.28 (1.46) | 3.05 (2.67) | 0.860 | | 3.38 (4.49) | 2.66 (5.69) | | 2.97 (4.58) | 2.68 (5.36) | | 2.83 (6.15) | 2.47 (15.01) | | Posterior (μm) | 0.76 (0.41) | 0.58 (0.37) | 0.081 | 0.77 (0.43) | 0.59 (0.37) | 0.072 | 0.72 (0.46) | 0.58 (0.37) | 0.309 | | 0.74 (1.68) | 0.57 (1.74) | | 0.71 (1.78) | 0.61 (1.73) | | 0.64 (1.72) | 0.65 (1.70) | | Posterior (μm) | 0.02 (0.41) | −0.02 (0.24) | 0.667 | 0.02 (0.44) | −0.01 (0.23) | 0.554 | −0.01 (0.40) | 0.00 (0.23) | 0.891 | | 0.09 (1.48) | 0.00 (1.04) | | 0.05 (1.98) | −0.03 (0.95) | | −0.01 (1.53) | −0.01 (1.00) | | Posterior (μm) | 0.11 (0.22) | 0.07 (0.23) | 0.386 | 0.10 (0.20) | 0.07 (0.19) | 0.462 | 0.10 (0.23) | 0.04 (0.17) | 0.298 | | 0.11 (0.92) | 0.03 (1.06) | | 0.12 (0.76) | 0.07 (0.80) | | 0.11 (1.13) | 0.04 (0.82) | |
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RMS: root mean square, HOA: higher order aberrations, LOA: lower order aberrations; : vertical coma; : horizontal coma; : spherical aberration. |