Research Article

Comparison of Long-Term Outcomes and Refractive Stability following SMILE versus SMILE Combined with Accelerated Cross-Linking (SMILE XTRA)

Table 1

Patient demographics and preoperative data.

Parameter (mean ± SD)SMILE (n = 54)SMILE XTRA (n = 54) value

Total no. of eyes5454
Total no. of patients2727
Male: female11 : 1612 : 15
Age (years)25.96 ± 2.7125.85 ± 4.060.90
Sphere (D)−4.24 ± 1.84−4.036 ± 1.940.56
Cylinder (D)−0.71 ± 0.68−0.95 ± 1.060.17
SE (D)−4.61 ± 1.98−4.41 ± 1.890.57
CDVA (logMAR)−0.06 ± 0.04−0.06 ± 0.050.85
K1 (D)42.67 ± 1.443.68 ± 1.77≤0.001
K2 (D)43.68 ± 1.4144.87 ± 1.54≤0.001
Astigmatism (D)1.02 ± 0.551.19 ± 0.730.19
CCT (μ)527.88 ± 29.47515.29 ± 26.450.02
Thinnest pachymetry (μ)523.83 ± 29.48510.27 ± 26.840.01

VisuMax diagnostic and treatment data
Sphere (D)−4.43 ± 1.9−4.23 ± 2.010.58
Cylinder (D)−0.80 ± 0.68−0.95 ± 1.10.39
Cap thickness (μ)120 ± 0120 ± 01.00
Optical zone (μ)6.36 ± 0.306.27 ± 0.290.14
Minimum lenticule thickness (μ)16.85 ± 8.2513.65 ± 6.420.02
Maximum lenticule thickness (μ)96.53 ± 22.9087.48 ± 21.700.03
RST (μ)314.13 ± 31.30303.75 ± 30.650.08

UDVA: uncorrected distance visual acuity; D: diopter; SE: spherical equivalent; CDVA: corrected distance visual acuity; K: keratometry; CCT: central corneal thickness; RST: residual stromal thickness.