Research Article

Treatment for Nontype 1 Retinopathy of Prematurity by Intravitreal Injection of Antivascular Endothelial Growth Factor Drugs

Table 1

Characteristics of subjects with type 1 and nontype 1 ROP (N  = 138).

ParametersαNontype type I ROP groupType 1 ROP groupStatistic valueβPβ
(N  = 39)(N  = 99)

GA (week)28.5 ± 1.928.9 ± 2.21.0330.303
BW (kg)1.16 ± 0.351.19 ± 0.370.5040.615
Gender (male, N (%))21 (53.8)65 (65.7)1.6620.197
Hospitalization days in NICU (day)56.3 ± 23.253.6 ± 28.80.5210.603
Time of the first treatment (week)39.8 ± 2.738.1 ± 2.63.4610.001
Follow-up time (week)29.5 ± 10.133.6 ± 15.41.5370.127
Anti-VEGF drugs (N (%))
 Ranibizumab5 (12.8)45 (45.5)12.8960.000
 Fusion proteins (conbercept and aflibercept)34 (87.2)54 (54.5)

αGA, gestational age; BW, birth weight. βDifference of gender was analyzed by the χ2 test, and the remaining parameters were tested using the t-test.