Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
Table 3
Barriers to medication adherence in children with pediatric glaucoma.
Barrier
Univariate analysis, odds ratio (95% confidence interval)
value
Multiple analysis, odds ratio (95% confidence interval)
value
Univariate analysis†, odds ratio (95% confidence interval)
value
Multiple analysis†, odds ratio (95% confidence interval)
value
Difficulty with acquisition of medications
2.708 (1.269–5.778)
0.010
1.652 (0.679–4.020)
0.268
2.533 (1.126–5.697)
0.025
1.671 (0.659–4.236)
0.279
Difficulty with medication schedule
2.593 (1.229–5.470)
0.012
1.260 (0.489–3.243)
0.632
2.252 (1.024–4.953)
0.043
1.514 (0.623–3.678)
0.360
Forgetfulness
1.876 (0.858–4.100)
0.115
1.733 (0.752–3.994)
0.197
Too many varieties of medications
2.467 (0.974–6.245)
0.057
1.812 (0.666–4.928)
0.244
High expenses for medications
4.697 (1.522–14.497)
0.007
2.768 (0.827–9.270)
0.099
4.768 (1.432–15.868)
0.011
3.354 (0.944–11.912)
0.061
Side effects of medications
3.415 (0.945–12.341)
0.061
3.488 (0.915–13.299)
0.067
Difficulty with medication instillation
2.619 (1.206–5.686)
0.015
1.623 (0.659–4.000)
0.292
2.048 (0.887–4.729)
0.093
Poor efficacy of medications
1.686 (0.804–3.534)
0.167
1.632 (0.735–3.626)
0.229
Skepticism of irreversible blindness resulted from glaucoma
1.900 (0.663–5.441)
0.232
1.248 (0.408–3.819)
0.697
Skepticism of the importance of medications in treating glaucoma
0.633 (0.160–2.510)
0.516
0.533 (0.129–2.194)
0.383
Resistance of children
1.997 (0.957–4.167)
0.065
1.467 (0.667–3.226)
0.340
Mistrust of ophthalmologists
2.229 (0.922–5.386)
0.075
2.417 (0.939–6.219)
0.067
Anxiety and depression
2.636 (1.091–6.371)
0.031
1.657 (0.642–4.281)
0.297
1.875 (0.744–4.729)
0.183
Number of barriers
1.213 (1.072–1.372)
0.002
1.175 (1.030–1.339)
0.016
Only barriers statistically significant in univariate analysis were analyzed for multiple analysis. †Adjusted for age and knowledge about pediatric glaucoma of caregivers.
