Statistical Analysis on Time to Blindness of Glaucoma Patients at Jimma University Specialized Hospital: Application of Accelerated Failure Time Model

Table 5

Multivariable analysis of glaucoma patient’s dataset at Jimma University specialized hospital, 2016–2020 (n = 321).

Covariates	Category	The semiparametric model of glaucoma patients at Jimma University Specialized Hospital, 2016–2020					The log-logistic accelerated failure time model of glaucoma patients at Jimma University Specialized Hospital, 2016–2020
		B	Exp (β)	St. Err(β)	value	95% CI for Exp (β)	Β	Exp (β)	St. Err (β)	value	95% CI for Exp (β)
Age	40–43 (ref)
	44–69	0.388	1.475	0.2384	0.1020	[0.924–2.353]	−0.229	0.794	0.133	0.084	[0.533–1.054]
		0.114	1.122	0.2752	0.6760	[0.678–2.011]	−0.039	0.961	0.154	0.797	[0.659–1.262]
Gender	Female (ref)
	Male	0.182	1.199	0.142	0.2039	[0.906–1.586]	−0.086	0.918	0.081	0.293	[0.759–1.076]
Stage of glaucoma	Early (ref)
	Moderate	0.337	1.399	0.250	0.1780	[0.921–2.461]	−0.109	0.896	0.143	0.443	[0.615–1.176]
	Advanced	0.041	1.041	0.276	0.8840	[0.602–1.778]	0.040	1.041	0.154	0.794	[0.739–1.342]
	Absolute	0.554	1.739	0.270	0.0400	[1.063–3.077]	0.886	2.425	0.090	0.049	[2.249–2.601]
Duration of diagnosis
	1–5 months	−0.558	0.572	0.163	0.0006	[0.426–0.812]	0.409	1.505	0.092	0.001	[0.228–0.589]
	≥6 months	−1.592	0.203	0.176	0.0010	[0.141–0.279]	1.111	3.037	0.095	0.001	[2.850–3.22]
Cup-disk ratio	≤0.7 (ref)
		0.133	1.141	0.1353	0.3260	[0.885–1.510]	0.039	1.039	0.079	0.623	[0.884–1.193]
IOP	Normal (ref)
	Not normal	0.133	1.143	0.134	0.320	[0.899–1.535]	−0.161	0.851	0.076	0.034	[0.702–0.999]
Type of medication	Timoglue (ref)
	Timolol	−0.039	0.961	0.158	0.8030	[−0.73–1.371]	0.0886	1.093	0.090	0.326	[0.916–1.269]
	Diamox	0.249	1.282	0.152	0.1030	[0.97–1.774]	−0.130	0.877	0.092	0.159	[0.696–1.057]
Diabetics	No (ref)
	Yes	0.039	1.039	0.138	0.7780	0.780–1.353	−0.039	0.961	0.079	0.619	[0.806–1.115]

Source: Jimma University Specialized Hospitals, Ethiopia; from January 1, 2016, to August 30, 2020, ref = reference group.