A Classification Tree Model with Optical Coherence Tomography Angiography Variables to Screen Early-Stage Diabetic Retinopathy in Diabetic Patients

Table 1

General and ocular characteristics of diabetic patients in two cohorts.

	Cohort 1			Cohort 2
	NDR	NPDR	value	NDR	NPDR	value
Eyes (n)	71	50	NA	70	50	NA
Age (years)	56.39 ± 11.01	57.00 ± 8.83	0.749	56.83 ± 10.62	57.61 ± 9.12	0.676
Sex (male: female)	43 : 28	31 : 19	0.873	41 : 29	26 : 24	0.475
HbAlc (%)	8.63 ± 2.17	8.83 ± 2.45	0.640	8.59 ± 2.09	9.22 ± 2.56	0.159
DM duration (years)	7.27 ± 6.77	11.46 ± 7.58	0.003	7.64 ± 6.92	11.50 ± 6.94	0.006
Presence of hypertension (n, %)	6, 8.45%	5, 10.00%	1.000	4, 5.71%	5, 10.00%	0.598
Severity (mild: moderate)	NA	20 : 30	NA	NA	24 : 26	NA
IOP (mmHg)	15.51 ± 2.52	15.38 ± 3.69	0.822	15.48 ± 2.72	15.17 ± 3.63	0.600
BVCA (LogMAR)	-0.0079 ± 0.11	0.10 ± 0.21	<0.001	0.0020 ± 0.10	0.072 ± 0.19	0.01
FAZ area (mm^2)	0.33 ± 0.12	0.37 ± 0.24	0.153	0.37 ± 0.26	0.41 ± 0.27	0.443
SCP density (%)	46.79 ± 3.83	43.71 ± 4.72	<0.001	46.51 ± 4.22	43.80 ± 4.32	0.001
DCP density (%)	46.18 ± 6.12	43.09 ± 6.32	0.008	45.52 ± 4.87	42.17 ± 6.18	0.001
RPCP density (%)	48.02 ± 3.13	46.43 ± 3.04	0.007	47.49 ± 4.00	46.27 ± 3.04	0.078

NDR, nondiabetic retinopathy; NPDR, nonproliferative diabetic retinopathy; NA, not available; DM, diabetes mellitus; IOP, intraocular pressure; BCVA, best corrected visual acuity; FAZ, foveal avascular zone; SCP, superficial capillary plexus; DCP, deep capillary plexus; RPCP, radial peripapillary capillary plexus. <0.05.