Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases

Figure 5

Nomogram construction for predicting overall survival in uveal melanoma. (a): The nomogram composed by the 3-miRNA score, stage, TNM, age, and gender. The total points were calculated by drawing a vertical line from variable values to the axis labelled “Points” which can predicted 1 and 3 years of overall survival (OS). (b): Calibration curves of the nomogram for predicting OS at 1 year (red solid line) and 3 years (blue solid line). (c): Calibration curves of the nomograms for predicting OS in without 3-miRNA model (red solid line) and 3-miRNA model (blue solid line). (d): ROC curve for the accuracy of nomogram. The whole nomogram (green solid line) had higher accuracy than the nomogram model without 3-miRNA risk score (red solid line). (e): Decision curve of the nomogram for 3 years of OS. The green line means the speculation that all patients survive in the 3 years. The gray line means the speculation that no patients survive in the 3-year. The red and blue line means the nomogram without 3-miRNA model and integrated nomogram model respectively. (f): The net reduction curves of the nomogram without 3-miRNA model (black solid line) and nomogram model (red solid line).

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