Influence of Light-Emitting Diode-Derived Blue Light Overexposure on Rat Ocular Surface

Figure 3

TEM in the cornea of rats. In the control group (a, b, e), TEM showed that the corneal flat epithelial cells were arranged in order. By contrast, decreased microvillus (d, g) and disordered stromal layer were observed (c, d) in the blue light group. Furthermore, vacuoles were found in the basal nuclei (g, black arrow head) compared to the unexposed group (e). Fewer desmosomes between adjacent cells were recorded after 4 weeks of blue light exposure (h, white arrow head) with mitochondria swollen, vacuolated, and cristae disappeared (h, black arrow) compared with the control group (f). Scales of magnification: (a–d): 4000x. (e, g): 700x. (f, h): 2000x.

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