Proinflammatory Cytokines Trigger the Onset of Retinal Abnormalities and Metabolic Dysregulation in a Hyperglycemic Mouse Model

Figure 1

Development of the hyperglycemic mouse model. Body weight and blood glucose levels were measured before and after the STZ injection. STZ administration caused a significant decrease in body weight (a) and a significant increase in blood glucose levels (b). The unpaired t-test test was used to determine statistical significance. Values represent mean ± SEM (n = 8 mice per group). ^∗∗ < 0.01, ^∗∗∗ < 0.001. Abbreviation- C: control mice, HG: hyperglycemic mice.

(a)

(b)