Efficacy and Predictive Factors of Oral Spironolactone Treatment in Chronic Central Serous Chorioretinopathy

Figure 2

Multimodal images of a 44-year-old man with chronic central serous chorioretinopathy for 4 months. (A) Fluorescein angiography image showing slight leak points. (B) Indocyanine green angiography image showing several areas of hyperfluorescence and hypofluorescence indicating choroidal hyperpermeability. (C) Optical coherence tomography angiography image (6 × 6 mm) of the choriocapillaris plexus. (D) Horizontal- and (E) vertical-enhanced depth optical coherence tomography images of a responder to spironolactone at baseline, centered on the fovea, showing foveal subretinal detachment accompanied by increased choroidal thickness at baseline (white stars) and an intact ellipsoid zone (white arrow). After spironolactone treatment, a gradual resolution of the subretinal fluid was observed after 1 month (F, G), and complete resolution of the subretinal detachment was observed after 3 months of spironolactone treatment, lasting up to 6 months (H, I).