Lack of Association of Bone Morphogenetic Protein 2 Gene Haplotypes with Bone Mineral Density, Bone Loss, or Risk of Fractures in Men

Table 2

The distribution of BMP2 SNP3 genotype and allele frequencies and odds ratio.

(a)

Genotypes	Patients (𝑛, %)	Controls (𝑛, %)
AA	12 (10.2)	32 (14.3)
AT	61 (51.7)	121 (54.0)
TT	45 (38.1)	71 (31.7)
Total	118	224
HWE 𝑃 value	0.19	0.09
Alleles
*A	0.36 (±0.029)	0.41 (±0.022)
*T	0.64	0.59

(b)

Allele/genotype	Odd ratios (95% confidence interval), 𝑃 value
*A versus *T	1.25 (0.90–1.73) 𝑃=0.18
AA versus AT	1.34 (0.65–2.79), 𝑃=0.43
AA versus TT	1.69 (0.79–3.62), 𝑃=0.17
AA versus AT + TT	1.47 (0.73–2.98), 𝑃=0.28
Armitage’s trend test	1.29, 𝑃=0.15