Table of Contents Author Guidelines Submit a Manuscript
Journal of Osteoporosis
Volume 2011, Article ID 702735, 4 pages
http://dx.doi.org/10.4061/2011/702735
Review Article

The Bone-Muscle Relationship in Men and Women

Department of Radiology and Biomedical Imaging, School of Medicine, University of California, San Francisco, San Francisco, CA 94143-0946, USA

Received 30 June 2011; Accepted 10 August 2011

Academic Editor: Pawel Szulc

Copyright © 2011 Thomas F. Lang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [55 citations]

The following is the list of published articles that have cited the current article.

  • Sylvia Kirchengast, and Johannes Huber, “Sex-specific associations between soft tissue body composition and bone mineral density among older adults,” Annals Of Human Biology, vol. 39, no. 3, pp. 206–213, 2012. View at Publisher · View at Google Scholar
  • Marco Brotto, and Eduardo L. Abreu, “Sarcopenia: Pharmacology of Today and Tomorrow,” Journal of Pharmacology and Experimental Therapeutics, vol. 343, no. 3, pp. 540–546, 2012. View at Publisher · View at Google Scholar
  • Janalee Isaacson, and Marco Brotto, “Physiology of Mechanotransduction: How Do Muscle and Bone “Talk” to One Another?,” Clinical Reviews in Bone and Mineral Metabolism, vol. 12, no. 2, pp. 77–85, 2013. View at Publisher · View at Google Scholar
  • Christopher M. Cirnigliaro, William A. Bauman, Michael F. La Fountaine, Steven C. Kirshblum, and Ann M. Spungen, “Low-dose baclofen therapy raised plasma insulin-like growth factor-1 concentrations, but not into the normal range in a predictable and sustained manner in men with chronic spinal cord injury,” Journal Of Spinal Cord Medicine, vol. 36, no. 5, pp. 476–482, 2013. View at Publisher · View at Google Scholar
  • Nabilla Sofia Mohd Kamil, Siti Zawiah Md Dawal, Nabilla Sofia Mohd Kamil, and Siti Zawiah Md Dawal, “Investigation of sitting postural angle and muscle activity on ageing women workforce during computer task,” Current Trends in Ergonomics, vol. 10, pp. 57–62, 2013. View at Publisher · View at Google Scholar
  • Sunyoung Kim, Chang Won Won, Byung Sung Kim, Hyun Rim Choi, and Min Young Moon, “The Association between the Low Muscle Mass and Osteoporosis in Elderly Korean People,” Journal of Korean Medical Science, vol. 29, no. 7, pp. 995–1000, 2014. View at Publisher · View at Google Scholar
  • Masato Yano, Naoyuki Kawao, Katsumi Okumoto, Yukinori Tamura, Kiyotaka Okada, and Hiroshi Kaji, “Fibrodysplasia Ossificans Progressiva-related Activated Activin-like Kinase Signaling Enhances Osteoclast Formation during Heterotopic Ossification in Muscle Tissues,” Journal of Biological Chemistry, vol. 289, no. 24, pp. 16966–16977, 2014. View at Publisher · View at Google Scholar
  • Astrid Slizewski, Eva Burger-Heinrich, Michael Francken, Joachim Wahl, and Katerina Harvati, “Pilot Study for Reconstruction of Soft Tissues: Muscle Cross-Sectional Area of the Forearm Estimated From Cortical Bone for a Neolithic Sample,” Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology, vol. 297, no. 6, pp. 1103–1114, 2014. View at Publisher · View at Google Scholar
  • Shane A. Lloyd, Charles H. Lang, Yue Zhang, Emmanuel M. Paul, Lacee J. Laufenberg, Gregory S. Lewis, and Henry J. Donahue, “Interdependence of Muscle Atrophy and Bone Loss Induced by Mechanical Unloading,” Journal of Bone and Mineral Research, vol. 29, no. 5, pp. 1118–1130, 2014. View at Publisher · View at Google Scholar
  • Sima Ataollahi Eshkoor, Siti Sa'adiah Hassan Nudin, and Chan Yoke Mun, “Does substance abuse contribute to further risk of falls in dementia,” Aging Neuropsychology and Cognition, vol. 21, no. 3, pp. 317–324, 2014. View at Publisher · View at Google Scholar
  • A. Ireland, T. Maden-Wilkinson, B. Ganse, H. Degens, and J. Rittweger, “Effects of age and starting age upon side asymmetry in the arms of veteran tennis players: a cross-sectional study,” Osteoporosis International, vol. 25, no. 4, pp. 1389–1400, 2014. View at Publisher · View at Google Scholar
  • Magnus K. Karlsson, Hakan Magnusson, Maria C. Coster, Tord vonSchewelov, Caroline Karlsson, and Bjorn E. Rosengren, “Patients With Hip Osteoarthritis Have a Phenotype With High Bone Mass and Low Lean Body Mass,” Clinical Orthopaedics and Related Research, vol. 472, no. 4, pp. 1224–1229, 2014. View at Publisher · View at Google Scholar
  • J. F. Griffith, L. Xu, and P. C. Leung, “The functional muscle-bone unit in subjects of varying BMD,” Osteoporosis International, vol. 25, no. 3, pp. 999–1004, 2014. View at Publisher · View at Google Scholar
  • Jasminka Z. Ilich, Owen J. Kelly, Julia E. Inglis, Lynn B. Panton, Gustavo Duque, and Michael J. Ormsbee, “Interrelationship among muscle, fat, and bone: Connecting the dots on cellular, hormonal, and whole body levels,” Ageing Research Reviews, 2014. View at Publisher · View at Google Scholar
  • D. Shin, S. Kim, K. H. Kim, and S. M. Park, “Importance of fat mass and lean mass on bone health in men: the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV),” Osteoporosis International, vol. 25, no. 2, pp. 467–474, 2014. View at Publisher · View at Google Scholar
  • K. A. Bolam, B. R. Beck, K. N. Adlard, T. L. Skinner, P. Cormie, D. A. Galvao, N. Spry, R. U. Newton, and D. R. Taaffe, “The relationship between BPAQ-derived physical activity and bone density of middle-aged and older men,” Osteoporosis International, vol. 25, no. 11, pp. 2663–2668, 2014. View at Publisher · View at Google Scholar
  • M. Yano, N. Kawao, Y. Tamura, K. Okada, and H. Kaji, “A Novel Factor, Tmem176b, Induced by Activin-like Kinase 2 Signal Promotes the Differentiation of Myoblasts into Osteoblasts,” Experimental and Clinical Endocrinology & Diabetes, vol. 122, no. 1, pp. 7–14, 2014. View at Publisher · View at Google Scholar
  • Hiroshi Kaji, “Interaction between Muscle and Bone,” Journal of Bone Metabolism, vol. 21, no. 1, pp. 29, 2014. View at Publisher · View at Google Scholar
  • Magnus K Karlsson, Håkan Magnusson, Thord von Schewelov, Maria Cöster, Caroline Karlsson, and Björn E Rosengren, “Patients with Osteoarthritis in all Three Knee Compartments and Patients with Medial Knee Osteoarthritis Have a Phenotype with High Bone Mass and High Fat Mass but Proportionally Low Lean Mass.,” The open orthopaedics journal, vol. 8, pp. 390–6, 2014. View at Publisher · View at Google Scholar
  • Magnus K Karlsson, Caroline Karlsson, Håkan Magnusson, Maria Cöster, Tord von Schewelov, Jan Åke Nilsson, Lars Brudin, and Björn E Rosengren, “Individuals with primary osteoarthritis have different phenotypes depending on the affected joint - a case control study from southern sweden including 514 participants.,” The open orthopaedics journal, vol. 8, pp. 450–6, 2014. View at Publisher · View at Google Scholar
  • A. -M. Liphardt, J. D. Schipilow, H. M. Macdonald, M. Kan, A. Zieger, and S. K. Boyd, “Bone micro-architecture of elite alpine skiers is not reflected by bone mineral density,” Osteoporosis International, vol. 26, no. 9, pp. 2309–2317, 2015. View at Publisher · View at Google Scholar
  • Didier Chalhoub, Peggy M. Cawthon, Kristine E. Ensrud, Marcia L. Stefanick, Deborah M. Kado, Robert Boudreau, Susan Greenspan, Anne B. Newman, Joseph Zmuda, Eric S. Orwoll, and Jane A. Cauley, “Risk of Nonspine Fractures in Older Adults with Sarcopenia, Low Bone Mass, or Both,” Journal of the American Geriatrics Society, 2015. View at Publisher · View at Google Scholar
  • Jaikitry Rawal, Mark J. W. McPhail, Gamumu Ratnayake, Pearl Chan, John Moxham, Stephen D. R. Harridge, Nicholas Hart, Hugh E. Montgomery, and Zudin A. Puthucheary, “A pilot study of change in fracture risk in patients with acute respiratory distress syndrome,” Critical Care, vol. 19, 2015. View at Publisher · View at Google Scholar
  • Marius Dettmer, and Stefan W. Kreuzer, “Bi-unicompartmental, robotic-assisted knee arthroplasty,” Operative Techniques in Orthopaedics, 2015. View at Publisher · View at Google Scholar
  • Ke Zhu, Jianxun Yi, Yajuan Xiao, Yumei Lai, Pingping Song, Wei Zheng, Hongli Jiao, Jie Fan, Chuanyue Wu, Di Chen, Jingsong Zhou, and Guozhi Xiao, “Impaired Bone Homeostasis in Amyotrophic Lateral Sclerosis Mice with Muscle Atrophy,” Journal Of Biological Chemistry, vol. 290, no. 13, pp. 8081–8094, 2015. View at Publisher · View at Google Scholar
  • Jingsong Zhou, Jianxun Yi, and Lynda Bonewald, “Muscle-Bone Crosstalk in Amyotrophic Lateral Sclerosis.,” Current osteoporosis reports, vol. 13, no. 5, pp. 274–9, 2015. View at Publisher · View at Google Scholar
  • Magnus K. Karlsson, Hakan Magnusson, Maria Coster, Caroline Karlsson, and Bjorn E. Rosengren, “Patients With Knee Osteoarthritis Have a Phenotype With Higher Bone Mass, Higher Fat Mass, and Lower Lean Body Mass,” Clinical Orthopaedics And Related Research, vol. 473, no. 1, pp. 258–264, 2015. View at Publisher · View at Google Scholar
  • Jennifer A. Cann, “Nonhuman Primate Models of Human Disease,” The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment, pp. 257–277, 2015. View at Publisher · View at Google Scholar
  • Seong Rae Kim, Kyung-Hyun Choi, Go-Un Jung, Doosup Shin, Kyuwoong Kim, and Sang Min Park, “Associations Between Fat Mass, Lean Mass, and Knee Osteoarthritis: The Fifth Korean National Health and Nutrition Examination Survey (KNHANES V),” Calcified Tissue International, 2016. View at Publisher · View at Google Scholar
  • Marco Brotto, Janalee Isaacson, and Eduardo L. Abreu, “The Muscle-Bone Connection,” Osteoporosis in Older Persons, pp. 59–92, 2016. View at Publisher · View at Google Scholar
  • Lisa Reider, Thomas Beck, Dawn Alley, Ram Miller, Michelle Shardell, John Schumacher, Jay Magaziner, Peggy M. Cawthon, Kamil E. Barbour, Jane A. Cauley, and Tamara Harris, “Evaluating the relationship between muscle and bone modeling response in older adults,” Bone, 2016. View at Publisher · View at Google Scholar
  • Qingfen Pan, Mary I. O’Connor, Richard D. Coutts, Sharon L. Hyzy, Rene Olivares-Navarrete, Zvi Schwartz, and Barbara D. Boyan, “Characterization of osteoarthritic human knees indicates potential sex differences,” Biology of Sex Differences, vol. 7, no. 1, 2016. View at Publisher · View at Google Scholar
  • Vera Zymbal, Kathleen F. Janz, and Fátima Baptista, “Sexual dimorphism in bone–muscle relationship in young adults,” Journal of Sports Sciences, pp. 1–6, 2016. View at Publisher · View at Google Scholar
  • Julie A. Pasco, Mohammadreza Mohebbi, Kara L. Holloway, Sharon L. Brennan-Olsen, Natalie K. Hyde, and Mark A. Kotowicz, “Musculoskeletal decline and mortality: prospective data from the Geelong Osteoporosis Study,” Journal of Cachexia, Sarcopenia and Muscle, 2016. View at Publisher · View at Google Scholar
  • Carolina Medina-Gomez, Denise HM Heppe, Jia-Lian Yin, Katerina Trajanoska, André G Uitterlinden, Thomas J Beck, Vincent WV Jaddoe, and Fernando Rivadeneira, “Bone Mass and Strength in School-Age Children Exhibit Sexual Dimorphism Related to Differences in Lean Mass: The Generation R Study,” Journal of Bone and Mineral Research, vol. 31, no. 5, pp. 1099–1106, 2016. View at Publisher · View at Google Scholar
  • Minseok Seo, Kelsey Caetano-Anolles, Sandra Rodriguez-Zas, Sojeong Ka, Jin Young Jeong, Sungkwon Park, Min Ji Kim, Whan-Gook Nho, Seoae Cho, Heebal Kim, and Hyun-Jeong Lee, “Comprehensive identification of sexually dimorphic genes in diverse cattle tissues using RNA-seq,” Bmc Genomics, vol. 17, 2016. View at Publisher · View at Google Scholar
  • Nor Azizah Ishak, Zarina Zahari, and Maria Justine, “Muscle Functions and Functional Performance among Older Persons with and without Low Back Pain,” Current Gerontology and Geriatrics Research, vol. 2016, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  • T.H. Kim, S.-H. Kim, J. Kim, and H.-J. Hwang, “Health-related quality of life and activity limitation in an elderly Korean population with sarcopenia: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV-2, 3), 2008–2009,” European Geriatric Medicine, 2017. View at Publisher · View at Google Scholar
  • Alex Ireland, Stella Muthuri, Joern Rittweger, Judith E Adams, Kate A Ward, Diana Kuh, and Rachel Cooper, “Later Age at Onset of Independent Walking Is Associated With Lower Bone Strength at Fracture-Prone Sites in Older Men.,” Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 32, no. 6, pp. 1209–1217, 2017. View at Publisher · View at Google Scholar
  • Tulika Tripathi, Prateek Gupta, Jitender Sharma, Priyank Rai, Vinod Kumar Gupta, and Navneet Singh, “Bone-specific alkaline phosphatase – a potential biomarker for skeletal growth assessment,” Journal of Orthodontics, pp. 1–7, 2017. View at Publisher · View at Google Scholar
  • Nivash Rugbeer, and Lebo Mogatla, “Stability Index as a Novel Risk Factor to Distinguish Fall-Risk Gender Differences among Institutionalized Elderly,” Ageing International, 2017. View at Publisher · View at Google Scholar
  • Huan Wang, Jianxun Yi, Xuejun Li, Yajuan Xiao, Kamal Dhakal, and Jingsong Zhou, “ALS-associated mutation SOD1 G93A leads to abnormal mitochondrial dynamics in osteocytes,” Bone, 2017. View at Publisher · View at Google Scholar
  • Christian Armah, Chrissie Stansie Abaidoo, Joshua Tetteh, Thomas Diby, Obed Ohene-Djan Atuahene, Nancy Darko, and Atta Kusi Appiah, “A preliminary anthropometric study of height and sex determination using percutaneous humeral and tibial lengths,” Australian Journal of Forensic Sciences, pp. 1–7, 2017. View at Publisher · View at Google Scholar
  • Andrew R Krause, Toni L Speacht, Yue Zhang, Charles H Lang, and Henry J Donahue, “Simulated space radiation sensitizes bone but not muscle to the catabolic effects of mechanical unloading.,” PloS one, vol. 12, no. 8, 2017. View at Publisher · View at Google Scholar
  • Alice Cheng, Zvi Schwartz, Adrian Kahn, Xiyu Li, Zhenxing Shao, Muyang Sun, Yingfang Ao, Barbara D. Boyan, and Haifeng Chen, “Advances in Porous Scaffold Design for Bone and Cartilage Tissue Engineering and Regeneration,” Tissue Engineering Part B: Reviews, 2018. View at Publisher · View at Google Scholar
  • Tori M. Stone, Jonathan E. Wingo, Brett S. Nickerson, and Michael R. Esco, “Comparison of Bioelectrical Impedance Analysis and Dual-Energy X-Ray Absorptiometry for Estimating Bone Mineral Content,” International Journal of Sport Nutrition and Exercise Metabolism, pp. 1–5, 2018. View at Publisher · View at Google Scholar
  • Didier Chalhoub, Robert Boudreau, Susan Greenspan, Anne B Newman, Joseph Zmuda, Andrew W Frank-Wilson, Nayana Nagaraj, Andrew R Hoffman, Nancy E Lane, Marcia L Stefanick, Elizabeth Barrett-Connor, Tien Dam, Peggy M Cawthon, Eric S Orwoll, and Jane A Cauley, “Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men,” Journal of Bone and Mineral Research, vol. 33, no. 9, pp. 1612–1621, 2018. View at Publisher · View at Google Scholar
  • Marcela A. Silva-Couto, Fernando F. Paiva, Carolina C. Alcântara, Thaianne Mata, Christiane L. Prado-Medeiros, Tania F. Salvini, and Thiago Luiz Russo, “Midfemoral Bone Volume of Walking Subjects with Chronic Hemiparesis Post Stroke,” Journal of Stroke and Cerebrovascular Diseases, 2018. View at Publisher · View at Google Scholar
  • Isaac Okai, Abena Adutwumwaa Pianim, Benjamin Arko-Boham, and Emmanuel Acheampong, “A model for height and sex prediction from percutaneous lengths of forearm bones,” Australian Journal of Forensic Sciences, pp. 1–10, 2018. View at Publisher · View at Google Scholar
  • Riad Nasr, Nathalie Al Rassy, Eric Watelain, Joseph Matta, Fabienne Frenn, Maroun Rizkallah, Ghassan Maalouf, César El Khoury, Abdel-Jalil Berro, and Rawad El Hage, “Muscular Maximal Strength Indices and Bone Variables in a Group of Elderly Women,” Journal of Clinical Densitometry, 2018. View at Publisher · View at Google Scholar
  • Francisco D. GurriThe International Encyclopedia of Biological Anthropology, pp. 1–2, 2018. View at Publisher · View at Google Scholar
  • Emma Pomeroy, Alison Macintosh, Jonathan C.K. Wells, Tim J. Cole, and Jay T. Stock, “Relationship between body mass, lean mass, fat mass, and limb bone cross-sectional geometry: Implications for estimating body mass and physique from the skeleton,” American Journal of Physical Anthropology, 2018. View at Publisher · View at Google Scholar
  • Rosebella A. Iseme, Mark McEvoy, Brian Kelly, Linda Agnew, Frederick R. Walker, Michael Boyle, and John Attia, “A Cross-Sectional Study of the Association between Autoantibodies and Qualitative Ultrasound Index of Bone in an Elderly Sample without Clinical Autoimmune Disease,” Journal of Immunology Research, vol. 2018, pp. 1–19, 2018. View at Publisher · View at Google Scholar
  • Jeehyun Kim, Hyuktae Kwon, Bo-Kyoung Heo, Hee-Kyung Joh, Cheol Min Lee, Seung-Sik Hwang, Danbee Park, and Jae-Hong Park, “The Association between Fat Mass, Lean Mass and Bone Mineral Density in Premenopausal Women in Korea: A Cross-Sectional Study,” Korean Journal of Family Medicine, vol. 39, no. 2, pp. 74, 2018. View at Publisher · View at Google Scholar
  • Anood Jamal Alshaali, Soha Abd El Aziz Abd El Aal, Amal Mohamad AlJaziri, Tamer Mohamed Farid Abdellatif, Manal Mohammad Omran Taryam, and Nahed AbdulKhaleq Monsef, “Vertebral Fractures among Patients Referred for Bone Densitometry Screening in Dubai Primary Health Care Facilities,” International Journal of Rheumatology, vol. 2019, pp. 1–5, 2019. View at Publisher · View at Google Scholar