Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX

Table 3

AUC values (standard error) for MOI, FI, and OST with osteoporosis (BMD-T-score ≤ −2.5) at the femoral neck in the development FPS (age 65-72, 𝑛=434) and fracture cohorts (age 45-79, 𝑁=300) and in the validation fracture cohort (𝑁=200) and OSTPRE validation cohort (age 58–69, 𝑛=943).

	FPS cohort age 65-72	Fracture development cohort	Fracture validation cohort	OSTPRE cohortage 58-69
MOI	0.67 (0.06)	0.75 (0.03)	0.67 (0.07)	0.79 (0.04)
FI	0.56 (0.06)	0.68 (0.04)	0.53 (0.08)	0.76 (0.04)
OST	0.63 (0.06)	0.79 (0.03)*	0.62 (0.07)	0.74 (0.05)

* 𝑃<.05, significant difference between OST and FI.
MOI: Mikkeli Osteoporosis Index.
FI: Fracture Index.
OST: Osteporosis Self-Assessment Tool.