Detecting Early Biomechanical Effects of Zoledronic Acid on Femurs of Osteoporotic Female Rats

Table 3

Stiffness coefficient (N/mm) at 9 and 12 months.

Group	Stiffness Coefficient
	9 months			12 months
	Animal	Measurement (N/mm)	Mean ± SD	Animal	Measurement (N/mm)	Mean ± SD
ODW	1	207.4	214.2 ± 19.0	11	218.4	236.2 ± 24.4
	2	201.0		12	272.4
	3	198.8		13	209.8
	4	219.2		14	235.6
	5	257.1		15	273.0
	6	211.6		16	222.5
	7	190.7		17	201.7
	8	225.9		18	236.9
	9	203.8		19	254.2
	10	226.5		20	237.5
OZA	31	160.2	158.2 ± 9.1	21	175.1	176.4 ± 6.7
	32	150.4		22	178.0
	33	157.5		23	179.8
	34	142.8		24	163.3
	35	175.0		25	182.4
	36	162.4		26	169.8
	37	166.0		27	187.9
	38	149.3		28	176.4
	39	161.1		29	177.3
	40	157.7		30	174.3
SDW	41	180.6	171.7 ± 15.3	51	212.1	219.1 ± 7.0
	42	171.7		52	231.7
	43	141.9		53	225.8
	44	176.1		54	217.6
	45	174.4		55	215.9
	46	165.0		56	213.3
	47	180.1		57	221.6
	48	154.3		58	221.3
	49	176.4		59	215.7
	50	196.5		60	216.4
SZA	71	134.3	130.1 ± 29.0	61	144.6	153.4 ± 12.3
	72	109.6		62	155.4
	73	130.9		63	148.5
	74	118.2		64	136.5
	75	109.1		65	147.2
	76	133.8		66	156.4
	77	164.7		67	170.4
	78	112.7		68	141.2
	79	95.9		69	158.8
	80	191.9		70	174.9