Potential Extensions of the US FRAX Algorithm

Table 2

Fracture outcomes over 10 years among Rochester, MN women and men ≥40 years of age at baseline, by precipitating trauma.

Fracture site	Women		Men
	Moderate 𝑛 (%)	Severe 𝑛 (%)	Moderate 𝑛 (%)	Severe 𝑛 (%)
Skull/face	1 (0.5%)	0 (0%)	0 (0%)	0 (0%)
Cervical spine	1 (0.5%)	1 (3%)	0 (0%)	0 (0%)
Other vertebrae—symptomatic^a	20 (11%)	2 (7%)	11 (8%)	0 (0%)
Other vertebrae—asymptomatic	68 (37%)	1 (3%)	96 (67%)	0 (0%)
Ribs	29 (16%)	4 (14%)	14 (10%)	4 (21%)
Sternum/clavicle/scapula	2 (1%)	4 (14%)	2 (1%)	1 (5%)
Proximal humerus^a	5 (3%)	2 (7%)	1 (1%)	2 (11%)
Other arm	4 (2%)	0 (0%)	2 (1%)	0 (0%)
Distal forearm^a	16 (9%)	2 (7%)	1 (1%)	2 (11%)
Hand/fingers	8 (4%)	4 (14%)	2 (1%)	2 (11%)
Pelvis	6 (3%)	0 (0%)	3 (2%)	2 (11%)
Proximal femur^a	12 (6%)	0 (0%)	5 (3%)	0 (0%)
Other leg	9 (5%)	3 (10%)	5 (3%)	3 (16%)
Feet/toes	4 (2%)	6 (21%)	1 (1%)	3 (16%)
Total	185	29	143	19

^aMajor osteoporotic fractures.