Clinical Study
Genetic Influence of Candidate Osteoporosis Genes in Saudi Arabian Population: A Pilot Study
Table 3
(a) Demographic data of TNFRSF11B (C_11869235_10) of AA, AG, and GG allele. (b) Statistical analysis of the TNFRSF11B (C_11869235_10) 3 alleles.
(a) |
| Parameter | AA (114) | AG (80) | GG (6) |
| Age years | | | 69.5±12 | BMD hip g/cm2 | | | | T score | | | | Z score | | | | BMD spine g/cm2 | | | | T score | | | | Z score | | | | No. of fractures (%) | 38 (33.3) | 25 (31.25) | 3 (50) |
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AA: homozygous for A allele, AG: heterozygous allele, and GG: homozygous for G allele.
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(b) |
| Parameter | Alleles | value (CI) |
| Age | AA versus AG AA + AG versus GG | 0.2 0.001(8.191–8.808) | BMD hip | AA versus AG AA + AG versus GG | 0.232 0.001(0.213–0.333) | BMD spine | AA versus AG AA + AG versus GG | 0.77 0.001 (0.16–0.291) | History of fractures | AA versus AG AA + AG versus GG | 0.009 (12.94–13.059) 0.001 (59.85–60.146) |
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